Fontana Angelo, Tramice Annabella, Cutignano Adele, D'Ippolito Giuliana, Gavagnin Margherita, Cimino Guido
Istituto di Chimica Biomolecolare (ICB)-CNR, Via Campi Flegrei 34, 80078 Pozzuoli, Napoli, Italy.
J Org Chem. 2003 Mar 21;68(6):2405-9. doi: 10.1021/jo026131v.
Biogenesis of the enantiomeric sesquiterpenes 1 and 5 of the marine nudibranch Doriopsilla areolata was investigated by feeding of [1-(13)C]glucose, [1,2-(13)C(2)]glucose, and [1,2-(13)C(2)]acetate. Evidence is presented that supports de novo origin of both compounds via mevalonic acid.
通过投喂[1-(13)C]葡萄糖、[1,2-(13)C(2)]葡萄糖和[1,2-(13)C(2)]乙酸盐，研究了海洋裸鳃亚目动物乳晕多角海牛（Doriopsilla areolata）对映体倍半萜1和5的生物合成。提供的证据支持这两种化合物通过甲羟戊酸从头合成。
