Yadav J S, Reddy B V S, Reddy Ch Srinivas, Rajasekhar K
Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad-500 007, India.
J Org Chem. 2003 Mar 21;68(6):2525-7. doi: 10.1021/jo026544w.
A variety of epoxides respond rapidly with potassium thiocyanate in [bmim]PF(6)-H(2)O (2:1) solvent system at room temperature under mild and convenient conditions to produce the corresponding thiiranes in high to quantitative yields. Enhanced rates, improved yields, and recyclability of ionic liquids are the remarkable features observed in ionic liquids (ILs). The use of ionic liquids for this transformation avoids the use of heavy metal halides as promoters and chlorinated hydrocarbons as solvents. The ionic liquid was recycled in five to six subsequent runs with gradual decrease in activity.
在温和便捷的条件下，多种环氧化合物在室温下于[bmim]PF(6)-H(2)O（2:1）溶剂体系中与硫氰酸钾迅速反应，以高至定量的产率生成相应的硫杂环丙烷。离子液体展现出反应速率加快、产率提高以及可循环利用等显著特性。在此转化过程中使用离子液体避免了使用重金属卤化物作为促进剂以及氯代烃作为溶剂。该离子液体在后续五到六次运行中可循环使用，但其活性会逐渐降低。
