Lo Re Vincent, Gluckman Stephen J
Division of Infectious Diseases, Department of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Am J Med. 2003 Feb 15;114(3):217-23. doi: 10.1016/s0002-9343(02)01495-x.
Eosinophilic meningitis is a rare clinical entity that can be useful in narrowing the differential diagnosis of central nervous system disease. It is defined by the presence of 10 or more eosinophils/microL in the cerebrospinal fluid (CSF) or a CSF eosinophilia of at least 10%. The most common cause is invasion of the central nervous system by helminthic parasites, particularly Angiostrongylus cantonensis, but other infections as well as noninfectious conditions may also be associated. This review describes the etiologies of eosinophilic meningitis, focusing primarily on the helminths that cause CSF eosinophilia.
嗜酸性粒细胞性脑膜炎是一种罕见的临床病症，有助于缩小中枢神经系统疾病的鉴别诊断范围。其定义为脑脊液（CSF）中每微升有10个或更多嗜酸性粒细胞，或脑脊液嗜酸性粒细胞增多至少10%。最常见的病因是蠕虫寄生虫侵入中枢神经系统，尤其是广州管圆线虫，但其他感染以及非感染性疾病也可能与之相关。本综述描述了嗜酸性粒细胞性脑膜炎的病因，主要聚焦于导致脑脊液嗜酸性粒细胞增多的蠕虫。
