Nakagawa M, Kawashima Y, Uchiyama M
Lipids. 1976 Mar;11(3):241-3. doi: 10.1007/BF02532864.
The relationship between desaturation and chain elongation of palmityl-CoA was studied in rat liver microsomes. Enzyme activities for desaturation and chain elongation were stimulated by re-feeding starved rats. The activities of desaturation and chain elongation in re-fed rats were four- and twofold greater than those in normal rats, respectively. When a sonicated dispersion of lecithin was added to the incubation medium containing both reactions, chain elongation activity, especially formation of stearic acid, was stimulated and desaturation activity was apparently depressed.
在大鼠肝脏微粒体中研究了棕榈酰辅酶A去饱和与链延长之间的关系。饥饿大鼠重新喂食可刺激去饱和及链延长的酶活性。重新喂食大鼠的去饱和及链延长活性分别比正常大鼠高4倍和2倍。当将卵磷脂的超声分散液添加到包含这两种反应的孵育培养基中时，链延长活性，尤其是硬脂酸的形成受到刺激，而去饱和活性明显受到抑制。
