Thrall Peter H, Burdon Jeremy J
Commonwealth Scientific and Industrial Research Organization (CSIRO)-Plant Industry, Centre for Plant Biodiversity Research, General Post Office Box 1600, Canberra, ACT 2601, Australia.
Science. 2003 Mar 14;299(5613):1735-7. doi: 10.1126/science.1080070.
In a wild plant-pathogen system, host resistance and pathogen virulence varied markedly among local populations. Broadly virulent pathogens occurred more frequently in highly resistant host populations, whereas avirulent pathogens dominated susceptible populations. Experimental inoculations indicated a negative trade-off between spore production and virulence. The nonrandom spatial distribution of pathogens, maintained through time despite high pathogen mobility, implies that selection favors virulent strains of Melampsora lini in resistant Linum marginale populations and avirulent strains in susceptible populations. These results are consistent with gene-for-gene models of host-pathogen coevolution that require trade-offs to prevent pathogen virulence increasing until host resistance becomes selectively neutral.
在一个野生植物 - 病原体系统中，宿主抗性和病原体毒力在当地种群间存在显著差异。广谱致病性病原体在高抗性宿主种群中出现得更为频繁，而无毒病原体在易感种群中占主导地位。实验接种表明，孢子产生与毒力之间存在负权衡。尽管病原体具有高迁移性，但病原体随时间保持的非随机空间分布意味着，选择有利于在抗性亚麻种群中的亚麻锈菌毒力菌株以及在易感种群中的无毒菌株。这些结果与宿主 - 病原体协同进化的基因对基因模型一致，该模型要求进行权衡以防止病原体毒力增加，直到宿主抗性变为选择性中性。
