Milánkovits Márton, Baksay László, Plachy János
Orv Hetil. 2002 Dec 22;143(51):2835-40.
Comparative, in vivo, human, prospective, single blind, clinical and microbiological diagnoses based and randomised study of the treatment of uncomplicated bacterial vaginosis with two forms of combined (metronidazole + nystatin + sulfadimidin) vaginal suppositories (laminated and mixed containing the same ingredients) and the standard preparations available in the Hungarian market (Dalacin vaginal cream and Klion vaginal suppository). The examinations involved 60 volunteers and were performed in the Gynecological Outpatient Clinic of the Council of Erd, the microbiological samples were examined at Saint Rókus Hospital in Budapest. The combined treatment was better tolerated and resulted in normal vaginal pH significantly more often at the same rate of recovery. The combined treatment is simultaneously effective in cases of the most prevalent coinfections too.
基于比较、体内、人体、前瞻性、单盲、临床和微生物学诊断的随机研究,比较两种形式(分层和混合,含相同成分)的联合(甲硝唑+制霉菌素+磺胺二甲嘧啶)阴道栓剂与匈牙利市场上现有的标准制剂(达力新阴道乳膏和克利翁阴道栓剂)治疗单纯性细菌性阴道病的效果。该研究涉及60名志愿者,在埃尔德理事会妇科门诊进行,微生物样本在布达佩斯的圣罗库斯医院检查。联合治疗耐受性更好,在相同恢复率的情况下,阴道pH值显著更常恢复正常。联合治疗对最常见的合并感染病例也同时有效。