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[Evaluation of the Surveillance System of Acute Flaccid Paralysis in Puglia: 5 years of work].

作者信息

Prato R, Labianca M, Calvario A, Bozzi A, Rizzo C, Fiore L, Vellucci L, Buttinelli G, Donati V, Lopalco P L, Germinario C

机构信息

Osservatorio Epidemiologico, Regione Puglia.

出版信息

Ann Ig. 2002 Nov-Dec;14(6):487-94.

PMID:12638352
Abstract

Surveillance of acute flaccid paralysis (AFP) is the milestone to monitor the progress toward poliomyelitis eradication aim, fixed by WHA in 1988. Active AFP surveillance started in Apulia in 1997; this work evaluates five-year period activities. In this period, the total number of cases notified was 48, 7 of which were resident out of Apulia. Twenty-five were males and 23 females; the age ranged between 1 month and 15 years. Any collected serum specimens showed protective antibody levels against polioviruses. Polioviruses type 1 and type 2 Sabin-like were isolated from stool samples collected from two AFP patients. AFP surveillance targets improved in the years, with only exception, in 2001, of second serum specimen collected within 14 days because of children were discharged earlier form the hospitals. Apulia experience demonstrates the achievement of good levels of AFP surveillance targets. System sensitivity has been optimal in 2001 with a number of notified cases threefold the expected value and adequate specimen sampling (80%). Additional involved hospitals and availability of increased and dedicated human resources contributed to this outcome. The effort to achieve WHO targets for AFP surveillance needs to be maintained in next years until global certification of eradication will be declared.

摘要

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Ann Ig. 2002 Nov-Dec;14(6):487-94.
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Hum Vaccin Immunother. 2017 Feb;13(2):332-338. doi: 10.1080/21645515.2017.1264726. Epub 2016 Dec 8.
2
Surveillance of acute flaccid paralysis (AFP) in Lombardy, Northern Italy, from 1997 to 2011 in the context of the national AFP surveillance system.1997年至2011年期间,在意大利北部伦巴第大区,于国家急性弛缓性麻痹(AFP)监测系统背景下开展的AFP监测。
Hum Vaccin Immunother. 2015;11(1):277-81. doi: 10.4161/hv.36164. Epub 2014 Nov 1.
3
Serological survey on immunity status against polioviruses in children and adolescents living in a border region, Apulia (Southern Italy).
对居住在意大利南部普利亚大区一个边境地区的儿童和青少年针对脊髓灰质炎病毒的免疫状况进行的血清学调查。
BMC Infect Dis. 2008 Oct 30;8:150. doi: 10.1186/1471-2334-8-150.