Oostvogel P M, Spaendonck M A, Hirasing R A, van Loon A M
Research Laboratory for Infectious Diseases, WHO Collaborating Centre for Reference and Research on Poliomyelitis, Rijks Instituut voor Volksgezondheid en Milieu (RIVM), Bilthoven, Netherlands.
Bull World Health Organ. 1998;76(1):55-62.
Detection and investigation of all cases of acute flaccid paralysis (AFP) in children below 15 years of age are among the criteria for poliomyelitis-free certification. In the absence of poliomyelitis the incidence of AFP is around 1 per 100,000 children aged < 15 years. In the Netherlands, surveillance of AFP began in October 1992 under the supervision of the Dutch Paediatric Surveillance System (NSCK). Over 90% of clinically active paediatricians participated in the monthly reporting of new cases of AFP. From October 1992 to December 1994 (27 months), 52 cases of AFP were reported. The incidence was 0.7 per 100,000 over the period, and reported cases were evenly distributed throughout the country. The main cause of AFP was Guillain-Barré syndrome. The average time between onset of symptoms and visiting a doctor was less than 3 days. The median reporting delay was 29 days, although the system was not intended as surveillance for action. Virological examination of faeces was carried out for only 40.4% of AFP patients. The start of the NSCK surveillance system coincided with the 1992-93 outbreak of poliomyelitis in the Netherlands, but only 7 of the 18 children with paralytic poliomyelitis were reported through the AFP surveillance system. For certification purposes, the present AFP surveillance system in the Netherlands needs to be improved with respect to coverage by including neurologists, rapidity of reporting, and completeness of laboratory investigations.
对15岁以下儿童的所有急性弛缓性麻痹(AFP)病例进行检测和调查是无脊髓灰质炎认证的标准之一。在没有脊髓灰质炎的情况下,AFP的发病率约为每10万名15岁以下儿童中有1例。在荷兰,AFP监测于1992年10月在荷兰儿科监测系统(NSCK)的监督下开始。超过90%的临床活跃儿科医生参与了AFP新病例的月度报告。从1992年10月到1994年12月(27个月),共报告了52例AFP病例。在此期间发病率为每10万分之0.7,报告病例在全国分布均匀。AFP的主要病因是吉兰 - 巴雷综合征。症状出现到就医的平均时间不到3天。报告延迟的中位数为29天,尽管该系统并非旨在作为行动监测。仅对40.4%的AFP患者进行了粪便病毒学检查。NSCK监测系统的启动与1992 - 1993年荷兰脊髓灰质炎疫情同时发生,但18例麻痹性脊髓灰质炎患儿中只有7例通过AFP监测系统报告。为了认证目的,荷兰目前的AFP监测系统需要在覆盖范围(包括神经科医生)、报告速度和实验室调查完整性方面加以改进。