Brachtel R
Med Klin. 1976 Mar 19;71(12):504-6.
A rare secondary effect of intramuscular injections is reported in three own observations: This embolia cutis medicamentosa has been relatively often found in former times as result of bismuthe and mercury injections during lues therapy and today is only occasionally found, especially after intramuscular injections of phenylbutazone-containing antirheumatics. The question is discussed whether this medicamental embolism is really due to an embolic occlusion of small skin arteries. The typical clinical picture of the infarct-resembling skin necrosis in livid skin area could also be explained by vessel necrosis or thrombosis in the site of injection itself.
这种药物性皮肤栓塞在以前由于梅毒治疗期间注射铋剂和汞剂而相对常见,如今仅偶尔出现,尤其是在肌肉注射含保泰松的抗风湿药之后。文中讨论了这种药物性栓塞是否真的是由于皮肤小动脉的栓塞性阻塞所致。在皮肤青紫区域出现类似梗死的皮肤坏死的典型临床表现,也可能是由注射部位本身的血管坏死或血栓形成所解释。