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药物性皮肤栓塞(作者译)

[Skin embolisation by drugs (author's transl)].

作者信息

Christ M

出版信息

Dtsch Med Wochenschr. 1980 Feb 8;105(6):201-3. doi: 10.1055/s-2008-1070634.

DOI:10.1055/s-2008-1070634
PMID:7353486
Abstract

After intragluteal injection of a drug mixture in a 39-year-old woman, circumscribed necroses developed at the site of injection. This is a rare complication of intramuscular administration of certain drugs, most of them antirheumatic agents. A haemorrhagic dermatitis develops, which may progress to necrosis. Healing occurs after spontaneous or surgical (deep excision) exclusion of the necrotic area with atrophic scarring. The complication is so rare that there is no requirement for the doctor to inform the patient of this possibility before injection. Nor is there liability by the doctor or the nurse who undertake the injections.

摘要

在一名39岁女性进行臀内注射药物混合物后,注射部位出现了局限性坏死。这是某些药物肌肉注射的一种罕见并发症,其中大多数是抗风湿药物。会出现出血性皮炎,可能会发展为坏死。在坏死区域自发或通过手术(深度切除)排除后,会形成萎缩性瘢痕而愈合。这种并发症非常罕见,以至于医生在注射前无需告知患者有这种可能性。进行注射的医生或护士也无需承担责任。

相似文献

1
[Skin embolisation by drugs (author's transl)].药物性皮肤栓塞(作者译)
Dtsch Med Wochenschr. 1980 Feb 8;105(6):201-3. doi: 10.1055/s-2008-1070634.
2
[Embolia cutis medicamentosa (author's transl)].药物性皮肤栓塞(作者译)
Med Klin. 1976 Mar 19;71(12):504-6.
3
[Circumscribed skin necroses following intramuscular injections. Review and case reports].[肌肉注射后局限性皮肤坏死。综述与病例报告]
MMW Munch Med Wochenschr. 1976 Nov 19;118(47):1515-8.
4
[Embolia cutis medicamentosa. Circumscribed skin necrosis following intramuscular injections].[药物性皮肤栓塞。肌肉注射后局限性皮肤坏死]
Med Welt. 1983 Dec 30;34(51-52):1450-3.
5
[Tissue necrosis following intramuscular administration of various drugs (Nicolau syndrome): clinical presentation, pathophysiology and treatment].[肌肉注射各种药物后发生的组织坏死(尼科劳综合征):临床表现、病理生理学及治疗]
Harefuah. 2009 Mar;148(3):186-8, 209.
6
Nicolau syndrome: a report of 2 cases.尼科劳综合征:2例报告。
J Drugs Dermatol. 2006 Apr;5(4):377-8.
7
[Circumscribed skin necrosis following intramuscular injection (embolia cutis medicamentosa)].
Praxis (Bern 1994). 1995 May 23;84(21):640-3.
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Nicolau syndrome aggravated by cold application after i.m. diclofenac.肌内注射双氯芬酸后冷敷加重尼科劳综合征。
J Dermatol. 2008 Jan;35(1):18-20. doi: 10.1111/j.1346-8138.2007.00404.x.
9
Heparin-induced cutaneous necrosis unrelated to injection sites. A sign of potentially lethal complications.
Arch Dermatol. 1983 May;119(5):400-3.
10
[Combined nerve damage and drug-induced cutaneous embolism after faulty intragluteal injection].[臀内注射失误后合并神经损伤及药物性皮肤栓塞]
Dtsch Med Wochenschr. 1983 Feb 11;108(6):221-3. doi: 10.1055/s-2008-1069531.

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