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使用脉搏血氧饱和度测定法检测先天性心脏病。

The use of pulse oximetry to detect congenital heart disease.

作者信息

Reich Jonathan D, Miller Sean, Brogdon Brenda, Casatelli Jennifer, Gompf Timothy C, Huhta James C, Sullivan Kevin

机构信息

Department of Pediatrics, Lakeland Regional Medical Center, Lakeland, FL 33805, USA.

出版信息

J Pediatr. 2003 Mar;142(3):268-72. doi: 10.1067/mpd.2003.87.

DOI:10.1067/mpd.2003.87
PMID:12640374
Abstract

OBJECTIVE

To evaluate whether pulse oximetry can be used as a screening test to detect congenital heart disease (CHD) in otherwise well newborns before nursery discharge.

METHODS

Births at Lakeland Regional Medical Center (LRMC) who met inclusion criteria, had a single pulse oximeter reading before discharge. A normal reading was considered to be >94%. Abnormal readings were repeated on a different extremity and if still abnormal, an echocardiography was performed. The number of children with CHD and the number of echocardiograms were compared with the previous year at LRMC.

RESULTS

There were 2114 infants enrolled, 88 echocardiograms (3.8%) were performed, and 43 were abnormal (yield = 48.9%), of which 12 required management (13.6%). The control group consisted of 2851 births, producing 108 echocardiograms (3.8%), 42 of which were abnormal (38.9%), and 13 required management (12.0%). No comparisons were significant. During both years, 3 children with cyanotic CHD were born. Routine pulse oximetry failed to detect a child with total anomalous pulmonary venous return. Not a single normal echocardiogram was generated by the study.

CONCLUSION

Routine pulse oximetry was nearly 100% specific for detecting cyanotic CHD; as a result there was no increase in the number of echocardiograms. Routine pulse oximetry did detect a child who might not have been detected otherwise but failed to detect one that should have been detected.

摘要

目的

评估脉搏血氧饱和度测定法能否作为一项筛查试验,用于在新生儿出院前检测无其他明显疾病的新生儿先天性心脏病(CHD)。

方法

在莱克兰地区医疗中心(LRMC)出生且符合纳入标准的婴儿,在出院前进行单次脉搏血氧饱和度测定。正常读数定义为>94%。异常读数在不同肢体上重复测量,若仍异常,则进行超声心动图检查。将患有CHD的儿童数量和超声心动图检查数量与LRMC上一年的数据进行比较。

结果

共纳入2114名婴儿,进行了88次超声心动图检查(3.8%),其中43次异常(检出率 = 48.9%),其中12例需要治疗(13.6%)。对照组有2851例出生,进行了108次超声心动图检查(3.8%),其中42次异常(38.9%),13例需要治疗(12.0%)。各项比较均无显著差异。在这两年中,有3例患有青紫型CHD的儿童出生。常规脉搏血氧饱和度测定法未能检测出一名完全性肺静脉异位引流患儿。该研究未产生一份正常的超声心动图检查结果。

结论

常规脉搏血氧饱和度测定法检测青紫型CHD的特异性接近100%;因此,超声心动图检查的数量没有增加。常规脉搏血氧饱和度测定法确实检测出了一名可能无法通过其他方式检测出的患儿,但未能检测出一名本应被检测出的患儿。

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