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在使用60钴、4兆伏、8兆伏、15兆伏、24兆伏峰值光子治疗扁桃体区癌症时,对相对射野中给定剂量进行不等权重分配。

Unequal weighting of given doses in opposed fields in treatment of cancer of the tonsillar region using 60Co, 4-, 8-, 15-, 24-MVp photons.

作者信息

Wollin M, Gilbert H A, Kagan A R

出版信息

Med Phys. 1976 Mar-Apr;3(2):113-6. doi: 10.1118/1.594276.

Abstract

Weighting of given doses from parallel opposed fields is a widespread practice in radiation therapy of cancer in the tonsillar region. In order to determine when weighting is useful, dose distributions on the central axis were calculated for various energies (60Co, 4-, 8-, 15-, and MVp photons), weighting factors, and field separations. Criteria for judging the usefulness of weighting were (i) that variation in the dose across the tumor volume not exceed 10%, and (ii) that the dose to critical tissues outside the target volume be at least 20% less than target volume dose. The clinical situation that met these criteria was a lateral lesion that extended to less than one-third of the transverse diameter of the head, treated with either 60Co, 8, or 4 MVp with 4:1 weighting. Under these conditions, weighting was considered to be justified.

摘要

在扁桃体区域癌症的放射治疗中,对来自平行相对野的给定剂量进行加权是一种广泛应用的做法。为了确定何时加权是有用的,针对各种能量(60Co、4、8、15和MVp光子)、加权因子和野间距,计算了中心轴上的剂量分布。判断加权有用性的标准是:(i) 肿瘤体积内剂量变化不超过10%,以及 (ii) 靶体积外关键组织的剂量比靶体积剂量至少低20%。符合这些标准的临床情况是,横向病变延伸至头部横径的不到三分之一,用60Co、8或4 MVp以4:1加权进行治疗。在这些条件下,加权被认为是合理的。

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