Kohler Kathryn A, Hlady W Gary, Banerjee Kaushik, Gupta Dhananjoy, Francis Paul, Durrani Sunita, Zuber Patrick L F, Sutter Roland W
Global Immunization Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Bull World Health Organ. 2003;81(1):2-9. Epub 2003 Mar 11.
To describe the characteristics of compatible poliomyelitis cases and to assess the programmatic implications of clusters of such cases in India.
We described the characteristics of compatible poliomyelitis cases, identified clusters of compatible cases (two or more in the same district or neighbouring districts within two months), and examined their relationship to wild poliovirus cases.
There were 362 compatible cases in 2000. The incidence of compatible cases was higher in districts with laboratory-confirmed poliomyelitis cases than in districts without laboratory-confirmed cases. Of 580 districts, 96 reported one compatible case and 72 reported two or more compatible cases. Among these 168 districts with at least one compatible case, 123 had internal or cross- border clusters of compatible cases. In 27 districts with clusters of compatible cases, no wild poliovirus was isolated either in the same district or in neighbouring districts. Three of these 27 districts presented laboratory-confirmed poliomyelitis cases during 2001.
Most clusters of compatible cases occurred in districts identified as areas with continuing wild poliovirus transmission and where mopping-up vaccination campaigns were carried out. As certification nears, areas with compatible poliomyelitis cases should be investigated and deficiencies in surveillance should be corrected in order to ensure that certification is justified.
描述符合脊髓灰质炎病例的特征，并评估印度此类病例聚集情况对规划的影响。
我们描述了符合脊髓灰质炎病例的特征，确定了符合病例的聚集情况（在两个月内在同一地区或相邻地区出现两例或更多），并研究了它们与野生脊髓灰质炎病毒病例的关系。
2000年有362例符合病例。有实验室确诊脊髓灰质炎病例的地区，符合病例的发病率高于无实验室确诊病例的地区。在580个地区中，96个地区报告了1例符合病例，72个地区报告了两例或更多符合病例。在这168个至少有1例符合病例的地区中，123个地区存在符合病例的内部或跨境聚集情况。在27个存在符合病例聚集情况的地区，同一地区或相邻地区均未分离出野生脊髓灰质炎病毒。这27个地区中有3个在2001年出现了实验室确诊的脊髓灰质炎病例。
大多数符合病例聚集情况发生在被确定为野生脊髓灰质炎病毒持续传播且开展扫荡式疫苗接种运动的地区。随着认证临近，应调查存在符合脊髓灰质炎病例的地区，并纠正监测中的缺陷，以确保认证合理。
