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支气管哮喘患儿使用吸附于氢氧化铝(阿勒皮拉尔)上的屋尘和螨提取物进行减敏治疗(作者译)

[Hyposensitization with extracts of house dust and mites adsorbed on aluminium-hydroxyde (allpyral) in children with bronchial asthma (author's transl)].

作者信息

Osváth P, Endre L

出版信息

Monatsschr Kinderheilkd (1902). 1976 Mar;124(3):110-3.

PMID:1264078
Abstract

Since the year 1971 the authors have treated 39 asthmatic patients with Allpyral house dust vaccins containing Dermatophagoides farinae extract. 16 of these children previously had similar treatment, but without mite extract, and this was changed because of the poor results. Patients allergic only to house dust and mites were selected according to the skin tests. Skin reaction to mite extract did not change even in symptomfree children in contrast to the decrease or disappearance of skin sensitivity to house dust. 23 out of 39 patients had no symptoms or only mild and short wheezing occasionaly in the last 3-6 months of treatment. There were six patients whose symptoms remained unchanged during the treatment. These children were all among the 16 asthmatics who previously had an unsuccessful house dust hyposensitization. So every patient whose treatment was started with the combined house dust-mite Allpyral has imporved, only 5 of the 23 still had yet a few asthmatic attacks.

摘要

自1971年以来,作者用含有粉尘螨提取物的Allpyral屋尘疫苗治疗了39例哮喘患者。其中16名儿童此前接受过类似治疗,但未使用螨提取物,由于效果不佳而改用这种治疗。根据皮肤试验选择仅对屋尘和螨过敏的患者。与对屋尘皮肤敏感性降低或消失形成对比的是,即使是无症状儿童,其对螨提取物的皮肤反应也没有变化。在治疗的最后3至6个月,39名患者中有23名没有症状,或仅偶尔有轻微和短暂的喘息。有6名患者在治疗期间症状没有变化。这些儿童都在之前屋尘脱敏治疗失败的16名哮喘患者之中。因此,每一位开始使用联合屋尘 - 螨Allpyral进行治疗的患者都有改善,23名患者中只有5名仍有几次哮喘发作。

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