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1
Hyposensitization with Dermatophagoides pteronyssinus antigen: trial in asthma induced by house dust.用屋尘螨抗原进行减敏治疗：对屋尘诱发的哮喘的试验
Br Med J. 1971 Oct 23;4(5781):204-6. doi: 10.1136/bmj.4.5781.204.
2
[Frequency of sensitization to D. pteronyssinus or D. farinae in children with perennial bronchial asthma].[常年性支气管哮喘患儿对屋尘螨或粉尘螨致敏的频率]
Monatsschr Kinderheilkd. 1985 Apr;133(4):214-8.
3
The effect of house dust mite specific immunotherapy on cysteinyl leukotriene production by blood leukocytes in subjects with perennial allergic rhinitis and asthma.屋尘螨特异性免疫疗法对常年性变应性鼻炎和哮喘患者血液白细胞半胱氨酰白三烯生成的影响。
J Investig Allergol Clin Immunol. 1998 Mar-Apr;8(2):98-104.
4
[Hyposensitization with extracts of house dust and mites adsorbed on aluminium-hydroxyde (allpyral) in children with bronchial asthma (author's transl)].支气管哮喘患儿使用吸附于氢氧化铝（阿勒皮拉尔）上的屋尘和螨提取物进行减敏治疗（作者译）
Monatsschr Kinderheilkd (1902). 1976 Mar;124(3):110-3.
5
Hyposensitization in asthmatics with mPEG-modified and unmodified house dust mite extract. IV. Occurrence and prediction of side effects.
Allergy. 1990 Feb;45(2):142-50. doi: 10.1111/j.1398-9995.1990.tb00472.x.
6
Hyposensitisation with house dust mite vaccine in bronchial asthma.支气管哮喘患者使用屋尘螨疫苗进行减敏治疗。
Br Med J. 1976 Sep 4;2(6035):561-2. doi: 10.1136/bmj.2.6035.561.
7
Hyposensitization with Dermatophagoides pteronyssinus in house dust allergy: a controlled study of clinical and immunological effects.屋尘螨诱发的室内灰尘过敏的减敏治疗：临床及免疫学效应的对照研究
Clin Allergy. 1973 Jun;3(2):177-93. doi: 10.1111/j.1365-2222.1973.tb01320.x.
8
Influence of hyposensitization with Dermatophagoides pteronyssinus extract on clinical score, total and specific IgE levels, and skin test in asthmatic patients.
Ann Allergy. 1985 Aug;55(2):150-2.
9
House dust mite hyposensitization.屋尘螨脱敏治疗
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10
Clinical study on value and limitations of subcutaneous immunotherapy (specific hyposensitization) in allergic asthma to house dust mite, based on a personal algorithm of selection.基于个人选择算法的皮下免疫疗法（特异性减敏）治疗屋尘螨过敏性哮喘的价值与局限性临床研究
J Investig Allergol Clin Immunol. 1991 Apr;1(2):145-53.

引用本文的文献

1
Mites and other indoor allergens - from exposure to sensitization and treatment.螨虫及其他室内过敏原——从暴露到致敏与治疗
Allergo J Int. 2015;24(3):68-80. doi: 10.1007/s40629-015-0049-1. Epub 2015 May 9.
2
House-dust allergy.室内尘螨过敏。
Can Fam Physician. 1982 Apr;28:738-42.
3
Immunotherapy in asthma.哮喘的免疫疗法
Thorax. 1997 Aug;52 Suppl 3(Suppl 3):S22-9. doi: 10.1136/thx.52.2008.s22.
4
Hyposensitization in asthma: a review.哮喘中的减敏疗法：综述
J R Soc Med. 1981 Jan;74(1):60-5.
5
Immunotherapy in respiratory allergy.呼吸道过敏的免疫疗法
Thorax. 1983 Jun;38(6):401-7. doi: 10.1136/thx.38.6.401.
6
House dust mites and allergy.屋尘螨与过敏
Arch Dis Child. 1972 Jun;47(253):327-9. doi: 10.1136/adc.47.253.327.
7
Standardized extracts, dust mite, and other arthropods (inhalants).标准化提取物、尘螨及其他节肢动物（吸入性变应原）。
Clin Rev Allergy. 1987 Feb;5(1):49-73. doi: 10.1007/BF02802257.
8
Inhalant allergy to arthropods. Clinical significance of arthropod allergy.节肢动物吸入性过敏。节肢动物过敏的临床意义。
Clin Rev Allergy. 1990 Spring;8(1):3-13. doi: 10.1007/BF02914433.
9
Immunotherapy in allergic respiratory diseases.过敏性呼吸道疾病的免疫疗法。
Lung. 1990;168 Suppl:1013-24. doi: 10.1007/BF02718239.
10
Mite allergy in Nigerians: studies on house dust mites in houses of allergic patients in Lagos.
Ir J Med Sci. 1978 Jan;147(1):26-30. doi: 10.1007/BF02939363.

本文引用的文献

1
Role of mites in allergy to house dust.螨虫在屋尘过敏中的作用。
Br Med J. 1968 Sep 14;3(5619):646-7. doi: 10.1136/bmj.3.5619.646.
2
House-dust mite asthma. Results of challenge tests on five criteria with Dermatophagoides pteronyssinus.屋尘螨性哮喘。用粉尘螨对五项标准进行激发试验的结果。
Br Med J. 1970 May 30;2(5708):501-4. doi: 10.1136/bmj.2.5708.501.
3
Mites and house-dust allergy.
Lancet. 1968 Jun 15;1(7555):1270-2. doi: 10.1016/s0140-6736(68)92290-3.
4
Mites and house-dust allergy in bronchial asthma.支气管哮喘中的螨类与屋尘过敏
Lancet. 1968 Jun 15;1(7555):1267-70. doi: 10.1016/s0140-6736(68)92289-7.

用屋尘螨抗原进行减敏治疗：对屋尘诱发的哮喘的试验

Hyposensitization with Dermatophagoides pteronyssinus antigen: trial in asthma induced by house dust.

作者信息

Smith A P

出版信息

Br Med J. 1971 Oct 23;4(5781):204-6. doi: 10.1136/bmj.4.5781.204.

DOI:10.1136/bmj.4.5781.204
PMID:4940158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1799252/
Abstract

A double-blind clinical trial of hyposensitization with aqueous extracts of Dermatophagoides pteronyssinus (the house-dust mite) and human skin scales showed a substantial improvement in symptoms in 11 asthmatics allergic to house dust treated with the D. pteronyssinus extract and a reduction in their need for other therapy. Five patients were well for a year but six relapsed. These results contrasted with the generally unfavourable course of the patients treated with the extract of human skin scales. Asthma due to house-dust allergy may be substantially improved by hyposensitization with D. pteronyssinus extract.

摘要

一项关于用屋尘螨（粉尘螨）水提取物和人皮肤鳞屑进行脱敏治疗的双盲临床试验表明，11名对屋尘过敏的哮喘患者在用粉尘螨提取物治疗后症状有显著改善，且对其他治疗的需求减少。5名患者病情好转了一年，但6名患者复发。这些结果与用人皮肤鳞屑提取物治疗的患者通常不佳的病程形成对比。用粉尘螨提取物进行脱敏治疗可使因屋尘过敏引起的哮喘得到显著改善。