用屋尘螨抗原进行减敏治疗：对屋尘诱发的哮喘的试验
Hyposensitization with Dermatophagoides pteronyssinus antigen: trial in asthma induced by house dust.
作者信息
Smith A P
出版信息
Br Med J. 1971 Oct 23;4(5781):204-6. doi: 10.1136/bmj.4.5781.204.
Abstract
A double-blind clinical trial of hyposensitization with aqueous extracts of Dermatophagoides pteronyssinus (the house-dust mite) and human skin scales showed a substantial improvement in symptoms in 11 asthmatics allergic to house dust treated with the D. pteronyssinus extract and a reduction in their need for other therapy. Five patients were well for a year but six relapsed. These results contrasted with the generally unfavourable course of the patients treated with the extract of human skin scales. Asthma due to house-dust allergy may be substantially improved by hyposensitization with D. pteronyssinus extract.
摘要
一项关于用屋尘螨（粉尘螨）水提取物和人皮肤鳞屑进行脱敏治疗的双盲临床试验表明，11名对屋尘过敏的哮喘患者在用粉尘螨提取物治疗后症状有显著改善，且对其他治疗的需求减少。5名患者病情好转了一年，但6名患者复发。这些结果与用人皮肤鳞屑提取物治疗的患者通常不佳的病程形成对比。用粉尘螨提取物进行脱敏治疗可使因屋尘过敏引起的哮喘得到显著改善。
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