累及皮肤的乳腺上皮样血管肉瘤：一种极易被误诊为乳腺癌的高度侵袭性肿瘤。
Epithelioid angiosarcoma of the breast involving the skin: a highly aggressive neoplasm readily mistaken for mammary carcinoma.
作者信息
Fariña M C, Casado V, Renedo G, Estévez L, Martín L, Requena L
机构信息
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
出版信息
J Cutan Pathol. 2003 Feb;30(2):152-6. doi: 10.1034/j.1600-0560.2003.00026.x.
BACKGROUND
Angiosarcomas are malignant neoplasms of endothelial cells. Angiosarcoma of the breast is a rare neoplasm that behaves in a highly malignant fashion. It must be differentiated from benign vascular proliferations and from mammary carcinoma.
METHODS
We report on a 49-year-old-woman who presented with a large mass involving the left breast.
RESULTS
The lesion had an erythematoviolaceous hue and livedoid pattern at the periphery. Histopathologic study showed an epithelioid malignant neoplasm, and immunohistochemical studies demonstrated that neoplastic cells expressed immunoreactivity for endothelial cell markers.
CONCLUSIONS
A diagnosis of epithelioid angiosarcoma of the breast was established. The patient was treated with radical mastectomy, but she refused any other additional therapy.
背景
血管肉瘤是内皮细胞的恶性肿瘤。乳腺血管肉瘤是一种罕见的肿瘤，具有高度恶性的行为。它必须与良性血管增生和乳腺癌相鉴别。
方法
我们报告了一名49岁女性，她左侧乳房出现一个大肿块。
结果
病变周边呈红紫色且有类紫癜样外观。组织病理学研究显示为上皮样恶性肿瘤，免疫组织化学研究表明肿瘤细胞对内皮细胞标志物呈免疫反应性。
结论
确诊为乳腺上皮样血管肉瘤。患者接受了根治性乳房切除术，但拒绝任何其他额外治疗。
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