Najean Y
Nouv Rev Fr Hematol. 1975 Jan-Feb;15(1):5-12.
Important discrepancies between the renewal rate of mature granulocytes measured by in vitro labelling with DF 32P and with sodium chromate 51Cr are observed. The possible explanations are reviewed: errors made in the drawing of the experimental curve of the radioactivity disappearance; labelling of long-living lymphocytes with chromium; elution of 32P; toxicity of DFP for the tagged cells. If the renewal-rate measured by using 51Cr is the real one, as it seems to be, currently accepted models of granulopoiesis will need reappraisal.
观察到用³²P-DF体外标记法和⁵¹Cr-铬酸钠法测定的成熟粒细胞更新率之间存在重要差异。对可能的解释进行了综述：放射性消失实验曲线绘制中的误差；铬对长寿淋巴细胞的标记；³²P的洗脱；DFP对标记细胞的毒性。如果用⁵¹Cr测量的更新率是真实的，就像看起来的那样，那么目前公认的粒细胞生成模型将需要重新评估。
