Jones Timothy J, Deal Dwight D, Vernon Jason C, Blackburn Noel, Stump David A
Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1009, USA.
Ann Thorac Surg. 2002 Dec;74(6):2132-7. doi: 10.1016/s0003-4975(02)04081-x.
Vacuum-assisted venous drainage enables adequate drainage through small-diameter cannulas but concerns are that it results in more gaseous microemboli delivered to the patient.
Five identical embolus detectors monitored the propagation of entrained air through a cardiopulmonary bypass (CPB) model. The ability of the CPB circuit to remove gaseous microemboli was studied with vacuum-assisted venous drainage and gravity siphon venous drainage using different pump speeds and rates of gaseous microemboli delivery.
Under all conditions entrained venous air resulted in the detection of gaseous microemboli in the perfusate after the arterial filter. In blood-primed circuits, increased flow rates and higher levels of vacuum-assisted venous drainage were independently associated with increased gaseous microemboli counts in the arterial line. Vacuum-assisted venous drainage at -40 mm Hg did not significantly increase gaseous microemboli activity when compared with gravity siphon venous drainage at 4 L/min flow rate.
Vacuum-assisted venous drainage at -40 mm Hg does not statistically reduce the ability of the CPB circuit to remove gaseous microemboli at lower pump rates. High levels of vacuum and increased pump flow rates should be avoided. Air should not be introduced into the venous line.
真空辅助静脉引流能够通过小口径插管实现充分引流,但有人担心这会导致更多气态微栓子进入患者体内。
五个相同的栓子探测器监测夹带空气在体外循环(CPB)模型中的传播。使用不同的泵速和气态微栓子输送速率,通过真空辅助静脉引流和重力虹吸静脉引流研究CPB回路清除气态微栓子的能力。
在所有情况下,夹带的静脉空气都会导致动脉滤器后的灌注液中检测到气态微栓子。在预充血液的回路中,流速增加和更高水平的真空辅助静脉引流与动脉管路中气态微栓子数量增加独立相关。与流速为4 L/min时的重力虹吸静脉引流相比,-40 mmHg的真空辅助静脉引流并未显著增加气态微栓子活性。
-40 mmHg的真空辅助静脉引流在统计学上不会降低CPB回路在较低泵速下清除气态微栓子的能力。应避免高真空度和增加泵流速。不应将空气引入静脉管路。