Vasquez Julio C, Vichiendilokkul Anna, Mahmood Syed, Baciewicz Frank A
Department of Cardiothoracic Surgery, Harper University Hospital, Wayne State University, Detroit, Michigan 48201, USA.
Ann Thorac Surg. 2002 Dec;74(6):2177-9. doi: 10.1016/s0003-4975(02)04125-5.
Heparin is the standard agent used for systemic anticoagulation during cardiopulmonary bypass in cardiac operations. Alternatives are needed when patients with heparin-induced thrombocytopenia type II are encountered. We present a patient with a clinical picture of heparin-induced thrombocytopenia type II who was effectively anticoagulated with bivalirudin, a direct thrombin inhibitor, during cardiopulmonary bypass for a cardiac operation.
肝素是心脏手术体外循环期间用于全身抗凝的标准药物。当遇到患有II型肝素诱导的血小板减少症的患者时，需要其他替代药物。我们报告了一名患有II型肝素诱导的血小板减少症临床表现的患者，在心脏手术的体外循环期间，使用直接凝血酶抑制剂比伐卢定进行了有效的抗凝。
