Alcaide Benito, Almendros Pedro
Departamento de Química Orgánica, Facultad de Química. Universidad Complutense de Madrid, 28040 Madrid, Spain.
Chemistry. 2003 Mar 17;9(6):1258-62. doi: 10.1002/chem.200390142.
Grubbs' carbene complex [Cl(2)(Cy(3)P)(2)Ru=CHPh] and its second-generation counterpart [Cl(2)(Im)(Cy(3)P)Ru=CHPh] have demonstrated remarkable efficiency metathesizing olefins. Furthermore, a growing number of newly discovered catalytic processes mediated by this complex broaden its synthetic utility beyond olefin metathesis. In addition, the ready availability of these stable ruthenium-based catalysts coupled with their tolerance toward a wide variety of common functional groups make Grubbs' catalysts very convenient synthetic tools. This paper presents recent advances in the non-metathetic behavior patterns of Grubbs' carbene.
格鲁布斯卡宾配合物[Cl(2)(Cy(3)P)(2)Ru=CHPh]及其第二代类似物[Cl(2)(Im)(Cy(3)P)Ru=CHPh]已显示出在烯烃复分解反应中具有显著的效率。此外，由该配合物介导的新发现的催化过程数量不断增加，拓宽了其在烯烃复分解反应之外的合成用途。此外，这些稳定的钌基催化剂易于获得，且对多种常见官能团具有耐受性，这使得格鲁布斯催化剂成为非常方便的合成工具。本文介绍了格鲁布斯卡宾非复分解行为模式的最新进展。
