Bilney Belinda, Morris Meg E, Perry Alison
School of Physiotherapy, Faculty of Health Science, La Trobe University, Victoria, 3086 Australia.
Neurorehabil Neural Repair. 2003 Mar;17(1):12-24. doi: 10.1177/0888439002250448.
This review provides a summary of the current literature examining the outcomes of physiotherapy, occupational therapy, and speech pathology interventions for people with Huntington's disease. The literature was retrieved via a systematic search using a combination of key words that included Huntington's disease, physiotherapy, occupational therapy, and speech pathology. The electronic databases for Medline, Embase, CINAHL, Cochrane Controlled Trials Register, and PEDro were searched up to May 2002. Articles meeting the review criteria were graded for study type and rated for quality using checklists to assess study validity and methodology. The majority of articles that examined therapy outcomes for people with Huntington's disease were derived from observational studies of low methodological quality. A low level of evidence exists to support the use of physiotherapy for addressing impairments of balance, muscle strength, and flexibility. There was a small amount of evidence to support the use of speech pathology for the management of eating and swallowing disorders. The current evidence is insufficient to make strong recommendations regarding the usefulness of physiotherapy, occupational therapy, or speech pathology for people with Huntington's disease. There is further need for therapy outcomes research in Huntington's disease so that clinicians may use evidence-based practice to assist clinical decision making.
本综述总结了目前有关针对亨廷顿舞蹈症患者的物理治疗、职业治疗和言语病理学干预效果的文献。通过使用包括亨廷顿舞蹈症、物理治疗、职业治疗和言语病理学在内的关键词组合进行系统检索来获取文献。检索了截至2002年5月的电子数据库,包括Medline、Embase、CINAHL、Cochrane对照试验注册库和PEDro。符合综述标准的文章根据研究类型进行分级,并使用清单评估研究有效性和方法来评定质量等级。大多数研究亨廷顿舞蹈症患者治疗效果的文章来自方法学质量较低的观察性研究。支持使用物理治疗来改善平衡、肌肉力量和灵活性障碍的证据水平较低。有少量证据支持使用言语病理学来管理进食和吞咽障碍。目前的证据不足以就物理治疗、职业治疗或言语病理学对亨廷顿舞蹈症患者的有用性做出有力推荐。亨廷顿舞蹈症的治疗效果研究还需要进一步开展,以便临床医生能够运用循证医学实践来辅助临床决策。