采用环孢素A成功治疗伴有t(6;8)(q15;q22)的红系发育不全骨髓增生异常综合征。
Successful treatment with cyclosporin A of myelodysplastic syndrome with erythroid hypoplasia associated with t(6;8)(q15;q22).
作者信息
Takata Shiro, Kojima Kensuke, Fujii Nobuharu, Kaneda Kinuyo, Yoshida Chikamasa, Hashimoto Daigo, Asakura Shoji, Shinagawa Katsuji, Tanimoto Mitsune
机构信息
Department of Medicine II, Okayama University Medical School, Okayama 700-8558, Japan.
出版信息
Cancer Genet Cytogenet. 2003 Jan 15;140(2):167-9. doi: 10.1016/s0165-4608(02)00655-6.
We report a t(6;8)(q15;q22) in a patient with myelodysplastic syndrome (MDS) with erythroid hypoplasia. The patient was successfully treated with an immunosuppressive treatment with cyclosporin A, while the translocation was repeatedly detected as the sole anomaly with the percentages of positive cells ranging from 5% to 70%. To our knowledge, the t(6:8) has never been described in MDS.
我们报告了1例患有红系发育不全的骨髓增生异常综合征（MDS）患者存在t(6;8)(q15;q22)。该患者接受环孢素A免疫抑制治疗后获得成功，而这种易位被反复检测为唯一异常，阳性细胞百分比在5%至70%之间。据我们所知，t(6;8)从未在MDS中被描述过。
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