Thorne Natasha, Amrein Hubert
Department of Molecular Genetics and Microbiology, Duke University Medical Center, 252 CARL Bldg./Research Drive, Durham, NC 27710, USA.
Curr Biol. 2003 Mar 18;13(6):R220-2. doi: 10.1016/s0960-9822(03)00154-4.
Pheromones are detected by the vomeronasal organ using members of two receptor superfamilies: the V1Rs and V2Rs. New studies show that MHC class I molecules are co-expressed in particular combinations with specific V2Rs in the vomeronasal organ. The role of these MHC molecules is unknown, but they may be of considerable biological significance.