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[根据卡莱亚罗-泰阿蒂尼法行水平声门切除术治疗累及喉前联合的肿瘤:肿瘤学及功能学结果]

[Horizontal glottectomy according to Calearo-Teatini for the treatment of tumors involving the anterior commissure of the larynx: oncological and functional results].

作者信息

Silvagni C, Romeo R, Grandinetti P, Ciofalo A, Re M

机构信息

Clinica Otorinolaringoiatrica, Università di Roma La Sapienza.

出版信息

Acta Otorhinolaryngol Ital. 2002 Dec;22(6):366-71.

Abstract

Among the different surgical options proposed for the treatment of glottic neoplasms involving the anterior commissure is the Horizontal Glottectomy (HG) proposed in 1978 by Calearo and Teatini. This type of laryngectomy is now included with good reason among the reconstructive horizontal laryngectomies in that it calls for the complete removal of the vocal folds and corresponding thyroid cartilage, with reconstruction of the airways by means of a thyrocricopexy. The object of our study was to describe the indications, surgical technique and oncological and functional results on the basis of the experience acquired by the Authors in 21 patients affected by laryngeal carcinoma (juxta-commissural T1a with diffuse hyperkeratosis of the contralateral cord and T1b infiltration to the anterior commissure) who underwent Horizontal Glottectomy (HG) according to the Calearo-Teatinin technique. For 3 of the 21 patients, the follow-up was under 3 years; for 11 patients it was over 5 years; and in 4 cases, it was over 10 years, with a survival rate at 5 years of 91.5%. There were 5 deaths (27.7%), 2 of which were due to non-neoplastic intervening causes, and 1 of which for a recurrence of N (5.5%) a year after surgery. In 3 patients, postoperative RT (radiotherapy) was carried out due to infiltration of the resection borders. With regard to the functional results, the naso-gastric tube was maintained for 8 days on average (min 4, max 12 days), and the tracheal cannula remained in situ an average of 11 days (min 7, max 19 days), while the average hospital stay was 9.3 days. The treatment options currently available for glottic tumors involving the anterior commissure may be divided among radiotherapy (RT), conventional surgery including vertical laryngectomies (Tucker's frontoanterior and Leroux-Robert's frontolateral laryngectomies) and horizontal laryngectomies (Calearo-Teatini's horizontal glottectomy, Majer-Piquet's crico-hyoido-epiglottopexy, and Labayle's crico-hyoidopexy), as well as endoscopic laser surgery. Each procedure is adopted on the basis of the experience and philosophy of the surgeon. For tumors involving the anterior commissure, our treatment protocol prescribes HG to be performed whenever possible, as its oncological and functional result have confirmed the validity of the procedure, as long as the indications are followed carefully. Furthermore, when compared to the frontolateral procedure, it provides similar oncological results, but being a much more economical operation on the vertical plane, it avoids stenotic complications, while, compared to the Majer-Piquet procedure, it allows easier and faster rehabilitation, even in elderly patients.

摘要

在为治疗累及前联合的声门肿瘤所提出的不同手术方案中,有1978年由卡莱罗(Calearo)和泰阿蒂尼(Teatini)提出的水平声门切除术(HG)。这种喉切除术现在被合理地纳入重建性水平喉切除术中,因为它要求完全切除声带及相应的甲状软骨,并通过甲状软骨固定术重建气道。我们研究的目的是根据作者在21例受喉癌影响的患者(对侧声带弥漫性角化过度的交界旁T1a和前联合浸润的T1b)中获得的经验,描述其适应症、手术技术以及肿瘤学和功能结果,这些患者根据卡莱罗 - 泰阿蒂尼技术接受了水平声门切除术(HG)。21例患者中有3例随访时间不足3年;11例患者随访时间超过5年;4例患者随访时间超过10年,5年生存率为91.5%。有5例死亡(27.7%),其中2例是由于非肿瘤性干预原因,1例是术后1年出现N复发(5.5%)。3例患者因切除边缘浸润接受了术后放疗(RT)。关于功能结果,鼻胃管平均留置8天(最短4天,最长12天),气管套管平均留置11天(最短7天,最长19天),而平均住院时间为9.3天。目前可用于累及前联合的声门肿瘤的治疗选择可分为放疗(RT)、包括垂直喉切除术(塔克氏额前喉切除术和勒鲁 - 罗伯特氏额外侧喉切除术)和水平喉切除术(卡莱罗 - 泰阿蒂尼氏水平声门切除术、马耶尔 - 皮凯氏环甲会厌固定术和拉拜勒氏环甲固定术)在内的传统手术,以及内镜激光手术。每种手术都是根据外科医生的经验和理念采用的。对于累及前联合的肿瘤,我们的治疗方案规定只要严格遵循适应症,只要有可能就应进行HG,因为其肿瘤学和功能结果已证实了该手术的有效性。此外,与额外侧手术相比,它提供了相似的肿瘤学结果,但在垂直平面上是一种更经济的手术,可避免狭窄并发症,而与马耶尔 - 皮凯手术相比,即使在老年患者中也能实现更轻松、更快的康复。

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