Department of Otolaryngology-Head and Neck Surgery, Azienda Ospedaliero-Universitaria Policlinico di Modena, Italy.
Am J Otolaryngol. 2011 Nov-Dec;32(6):578-82. doi: 10.1016/j.amjoto.2010.11.016. Epub 2011 Feb 8.
The aim of the study is to illustrate our experience with horizontal glottectomy (HG), reviewing the indications and results of this uncommon partial laryngectomy.
It is a retrospective study. We completed a chart review of patients who underwent partial laryngectomy between May 2003 and June 2010. Patients who underwent HG were included in the study. Data obtained were collected and analyzed.
Seven male patients were included in the study (mean age was 78 years; range, 69-88 years). In all cases, the TNM classification was pT1bN0M0 apart from one patient who had pT1N1M0. Three patients had a moderately differentiated neoplasm (G2), whereas 4 patients had a well-differentiated tumor (G1). Tracheotomy tube removal, oral feeding, and voice analysis have been evaluated and reported in the study. Mean follow-up was 16 months.
Horizontal glottectomy might be a worthwhile treatment option in selected patients nowadays. In older patients with anterior commissure involvement, this procedure guarantees adequate functional and good oncological results. This study may possibly help surgeons dealing with glottic cancer involving the anterior commissure because we believe that some patients could benefit from HG, even in this radiotherapy and transoral laser surgery "era."
本研究旨在阐述我们在水平部分喉切除术(HG)方面的经验,回顾这种不常见的部分喉切除术的适应证和结果。
这是一项回顾性研究。我们对 2003 年 5 月至 2010 年 6 月期间接受部分喉切除术的患者进行了病历回顾。对接受 HG 的患者进行了研究。收集并分析了获得的数据。
共有 7 名男性患者纳入研究(平均年龄 78 岁;范围,69-88 岁)。除 1 例患者为 pT1N1M0 外,所有患者的 TNM 分期均为 pT1bN0M0。3 例患者为中分化肿瘤(G2),4 例患者为高分化肿瘤(G1)。研究中评估并报告了气管造口管拔除、经口进食和嗓音分析的情况。平均随访时间为 16 个月。
对于现今的某些特定患者,水平部分喉切除术可能是一种有价值的治疗选择。对于累及前连合的老年患者,该手术可保证足够的功能和良好的肿瘤学结果。这项研究可能有助于处理累及前连合的声门癌的外科医生,因为我们相信,即使在放疗和经口激光手术的“时代”,仍有一些患者可以从 HG 中获益。