Anderson Lucy A, Orchardson Robin
Laboratory of Human Anatomy, Institute of Biomedical and Life Sciences, Thomson Building, University of Glasgow, UK.
Arch Oral Biol. 2003 Mar;48(3):201-4. doi: 10.1016/s0003-9969(02)00214-5.
Gum chewing increases salivary flow rate and pH. The aim of this study was to compare the effects of chewing standard sugar-free gum with those of a gum containing sodium bicarbonate.
Whole mouth saliva was collected from 20 volunteers who met inclusion criteria and gave informed consent. After unstimulated saliva was collected, stimulated saliva was collected at intervals during 30 min of chewing either a standard, mint-flavoured gum or bicarbonate-containing, mint-flavoured gum. The salivary flow and pH were measured for each sample.
With the standard gum, the mean peak salivary flow rate was 3.1+/-1.27 ml/min and the peak salivary pH was 7.39+/-0.14. With the bicarbonate gum, the peak flow rate was 2.79+/-1.38 ml/min and the peak salivary pH was 8.06+/-0.18. The salivary flow rates with the two gums were not significantly different; however, the increase in salivary pH was significantly greater for the bicarbonate gum.
The increased salivary pH with bicarbonate gum may have implications for oral health and prevention of dental caries.
咀嚼口香糖可增加唾液流速和pH值。本研究的目的是比较咀嚼标准无糖口香糖与含碳酸氢钠口香糖的效果。
从20名符合纳入标准并签署知情同意书的志愿者中收集全口唾液。在收集非刺激性唾液后,在咀嚼标准薄荷味口香糖或含碳酸氢钠薄荷味口香糖的30分钟内,每隔一段时间收集刺激性唾液。测量每个样本的唾液流速和pH值。
使用标准口香糖时,唾液平均峰值流速为3.1±1.27毫升/分钟,唾液峰值pH值为7.39±0.14。使用含碳酸氢钠口香糖时,峰值流速为2.79±1.38毫升/分钟,唾液峰值pH值为8.06±0.18。两种口香糖的唾液流速没有显著差异;然而,含碳酸氢钠口香糖的唾液pH值升高幅度明显更大。
含碳酸氢钠口香糖使唾液pH值升高可能对口腔健康和预防龋齿有影响。