黄嘌呤衍生物类新药的研究。第四十部分。7-氨氧基烷基茶碱。
The search for new drugs in the group of xanthine derivatives. Part XL. 7-Aminoxyalkyltheophyllines.
作者信息
Drabczyńska A, Eckstein M
出版信息
Pol J Pharmacol Pharm. 1976 Jan-Feb;28(1):95-103.
PMID:1264862
Abstract
7-Aminoxyalkyltheophyllines 4-6 were obtained in good yield by acidolysis or hydrazinolysis of 7-phtalimidoxyalkyltheophyllines 1-3. The structure of obtained compounds was confirmed on chemical routs by preparing typical derivatives (acyl, and oximes) and by UV, IR and NMR spectra.
摘要
通过7-邻苯二甲酰亚胺氧基烷基茶碱1-3的酸解或肼解反应，以良好的产率获得了7-氨基氧基烷基茶碱4-6。通过制备典型衍生物（酰基和肟）以及紫外、红外和核磁共振光谱，从化学途径确认了所得化合物的结构。
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