Evereklioglu Cem, Er Hamdi, Bekir Necdet A, Borazan Mehmet, Zorlu Ferhat
Department of Ophthalmology, Erciyes University Medical Faculty, Kayseri, Turkey.
J Cataract Refract Surg. 2003 Feb;29(2):301-8. doi: 10.1016/s0886-3350(02)01526-2.
To analyze and compare the outcomes and complication rates of secondary implantation of flexible, open-loop, anterior chamber intraocular lenses (AC IOLs) and single-piece, scleral-fixated, posterior chamber IOLs (PC IOLs).
Departments of Ophthalmology, Gaziantep University Medical Faculty, Research Hospital, Gaziantep, and Inönü University Medical Faculty, Research Hospital, Malatya, Turkey.
This study comprised 124 eyes of 113 aphakic patients (61 men, 52 women) with insufficient capsule support who had secondary IOL implantation from January 1997 to June 2001. In Group 1 (n = 73 eyes), a flexible, open-loop AC IOL was implanted and in Group 2 (n = 51 eyes), a single-piece, scleral-fixated PC IOL. The mean follow-up was 34 months (range 6 to 53 months) and took place at several different clinical settings. The mean interval between the initial cataract operation and secondary IOL implantation was 63 months (range 6 months to 12 years). The postoperative outcomes, safety, efficacy, and complication rates were analyzed, and the preoperative and postoperative best spectacle-corrected visual acuities (BSCVAs) were compared.
The postoperative mean BSCVA was 20/34.8 +/- 45.2 (SD) in Group 1 and 20/32.1 +/- 33.7 in Group 2; the difference was not significant (P =.718). A BSCVA of 20/40 or better was achieved in 62 eyes (84.9%) in Group 1 and 45 eyes (88.2%) in Group 2. A BSCVA of 20/25 or better was achieved in 40 eyes (54.8%) and 33 eyes (64.7%), respectively. The difference between the 2 groups was not significant (P =.472). Complications occurred in 25 eyes (34.2%) in Group 1 and 13 eyes (25.5%) in Group 2 (P >.05). The most frequent complications in Group 1 were early transient corneal edema, intraocular pressure elevation, cystoid macular edema, hyphema, secondary glaucoma, and iris capture or pupil decentration and in Group 2, suture erosion, a tilted or decentered IOL, fibrin reaction, and vitreous prolapse into the anterior chamber.
The AC IOLs and PC IOLs were safe and effective for secondary implantation to correct aphakia. Secondary implantation of the scleral-fixated PC IOL seemed to provide a more favorable outcome and a lower complication rate than the open-loop AC IOL in complicated cataract cases with inadequate capsule and zonular support. As scleral-fixated PC IOL implantation is technically more difficult than AC IOL implantation, the decisive factor in choosing a secondary IOL is surgical experience. Long-term comparison of both techniques is required.
分析并比较可折叠式开环前房型人工晶状体(AC IOL)二期植入与一体式巩膜固定后房型人工晶状体(PC IOL)二期植入的手术效果及并发症发生率。
土耳其加济安泰普大学医学院研究医院眼科以及马拉蒂亚伊诺努大学医学院研究医院眼科。
本研究纳入了1997年1月至2001年6月间接受二期人工晶状体植入的113例无晶状体眼患者(61例男性,52例女性)的124只眼,这些患者均存在晶状体囊支持不足的情况。第1组(n = 73只眼)植入可折叠式开环AC IOL,第2组(n = 51只眼)植入一体式巩膜固定PC IOL。平均随访时间为34个月(范围6至53个月),随访在多个不同临床机构进行。初次白内障手术与二期人工晶状体植入的平均间隔时间为63个月(范围6个月至12年)。分析术后效果、安全性、有效性及并发症发生率,并比较术前及术后最佳矫正视力(BSCVA)。
第1组术后平均BSCVA为20/34.8±45.2(标准差),第2组为20/32.1±33.7;差异无统计学意义(P = 0.718)。第1组62只眼(84.9%)、第2组45只眼(88.2%)达到20/40或更好的BSCVA。第1组40只眼(54.8%)、第2组33只眼(64.7%)达到20/25或更好的BSCVA。两组间差异无统计学意义(P = 0.472)。第1组25只眼(34.2%)、第2组13只眼(25.5%)发生并发症(P>0.05)。第1组最常见的并发症为早期短暂性角膜水肿、眼压升高、黄斑囊样水肿、前房积血、继发性青光眼以及虹膜夹持或瞳孔偏移,第2组为缝线侵蚀、人工晶状体倾斜或偏心、纤维蛋白反应以及玻璃体脱入前房。
AC IOL和PC IOL二期植入矫正无晶状体眼安全有效。在晶状体囊和悬韧带支持不足的复杂白内障病例中,巩膜固定PC IOL二期植入似乎比开环AC IOL能提供更良好的手术效果及更低的并发症发生率。由于巩膜固定PC IOL植入在技术上比AC IOL植入更困难,选择二期人工晶状体的决定性因素是手术经验。两种技术需要进行长期比较。