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冠状动脉供血不足的病理生理学与临床(作者译)

[Pathophysiology and clinic of coronary insufficiency (author's transl)].

作者信息

Wagner J

出版信息

Radiologe. 1976 Mar;16(3):89-93.

PMID:1265249
Abstract

Coronary insufficiency is defined. Some specialities of coronary circulation and aspects of their regulation are discussed. Physical mechanisms such as arteriovenous pressure gradient, vascular and extravascular components of the coronary resistance, the influence of rhythm change on the contraction-conditions of the myocardium, as well as the pulse-rate are differentiated from biological regulation mechanism, such as metabolic, nervous and hormone influences. The typical distrubance of this regulation in the coronary insufficiency is emphasized including impaired left ventricular function. In the second part, the clinic or coronary insufficiency deducted from the anatomical-pathological lesions as well as their pathophysical relations is dealt with, for instance manifestation of angina pectoris and myocardial infarct. The indications and contra-indications for selective coronary angiography are described.

摘要

对冠状动脉供血不足进行了定义。讨论了冠状动脉循环的一些特点及其调节方面。诸如动静脉压力梯度、冠状动脉阻力的血管和血管外成分、节律变化对心肌收缩条件的影响以及脉搏率等物理机制,与代谢、神经和激素影响等生物调节机制有所不同。强调了冠状动脉供血不足时这种调节的典型紊乱,包括左心室功能受损。在第二部分中,探讨了从解剖病理病变及其病理生理关系推导出来的冠状动脉供血不足的临床情况,例如心绞痛和心肌梗死的表现。描述了选择性冠状动脉造影的适应证和禁忌证。

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