Gralino B J, Porter J M, Rosch J
Radiology. 1976 May;119(2):301-5. doi: 10.1148/119.2.301.
Five patients with frostbite injury were studied by selective angiography and treated by selective intra-arterial application of reserpine with follow-up angiography two days later. Control angiograms showed various degrees of vascular spasm as well as organic stenosis and occlusion. Intra-arterial reserpine produced dramatic subsiding of vasospasm, as evidenced by angiography and relief of clinical symptoms. Complete healing without tissue loss occurred in 4 patients. Amputation was necessary in one case, due at least in part to pre-existing peripheral atherosclerotic disease. Selective angiography was found to contribute significantly to both the diagnosis and therapy of frostbite injury.
对5例冻伤患者进行了选择性血管造影研究，并通过选择性动脉内注射利血平进行治疗，两天后进行随访血管造影。对照血管造影显示出不同程度的血管痉挛以及器质性狭窄和闭塞。动脉内注射利血平使血管痉挛显著缓解，血管造影和临床症状的缓解均证明了这一点。4例患者实现了完全愈合且无组织损失。1例患者因至少部分由于先前存在的外周动脉粥样硬化疾病而需要截肢。结果发现，选择性血管造影对冻伤的诊断和治疗均有显著贡献。
