Harrison R W
University of Rochester School of Medicine, Rochester, New York 14642, USA.
J Natl Med Assoc. 2001 Mar;93(3 Suppl):6S-7S.
Pharmaceutical development and medical research continues at a fevered pitch. Historically, however, African Americans and other minorities have not been adequately represented in the studies determining a drug's safety and efficacy in humans. A history of misuse in the medical research systems (most notably the Tuskeegee study of syphillis in a population of illiterate, poor black men) have left many blacks wary of the health care system. However, attempts to address the health disparities faced by African Americans must include processes for including wider representation of blacks--as patients as well as investigators--in clinical trials.
药物研发和医学研究仍在狂热地进行着。然而，从历史上看，在确定药物对人体的安全性和有效性的研究中，非裔美国人和其他少数族裔并未得到充分体现。医学研究系统中存在的滥用历史（最著名的是对一群文盲、贫穷黑人男性进行的梅毒塔斯基吉研究）让许多黑人对医疗保健系统持谨慎态度。然而，解决非裔美国人所面临的健康差距问题的努力必须包括让更多黑人——作为患者和研究人员——参与临床试验的过程。
