Durrani A J, Moir G C, Diaz-Cano S J, Cerio R
Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK.
Br J Dermatol. 2003 Mar;148(3):569-72. doi: 10.1046/j.1365-2133.2003.05182.x.
The incidence of malignant melanoma (MM) is continuing to rise, although childhood MM remains rare. We describe an 8-year-old Afro-Caribbean girl who developed a non pigmented lesion on the tip of her left thumb, which persisted despite treatment in primary care with cryotherapy. At biopsy she was found to have an acquired acral MM. She underwent amputation of the distal phalanx of her thumb, together with positive sentinel lymph node (SLN) biopsy and subsequent axillary lymph node clearance and adjuvant chemotherapy. MMs are very rare in this age and skin-type group, therefore requiring strict diagnostic criteria. These criteria include the distinction from MM mimics, especially Spitz tumours, and an appropriate use of staging techniques such as SLN biopsy to influence management.
恶性黑色素瘤（MM）的发病率持续上升，尽管儿童期MM仍然罕见。我们描述了一名8岁的非洲加勒比裔女孩，她的左手拇指尖出现了一个无色素病变，尽管在基层医疗中接受了冷冻治疗，但该病变仍持续存在。活检时发现她患有获得性肢端MM。她接受了拇指远节指骨截肢术，同时进行了前哨淋巴结（SLN）活检阳性，随后进行了腋窝淋巴结清扫和辅助化疗。MM在这个年龄和皮肤类型组中非常罕见，因此需要严格的诊断标准。这些标准包括与MM模仿物（尤其是斯皮茨瘤）相区分，以及适当地使用分期技术（如SLN活检）来影响治疗管理。
