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微纤维胶原用于下咽血管瘤喉显微手术中的止血

Microfibrillar collagen for hemostasis in laryngomicrosurgery of hypopharyngeal hemangioma.

作者信息

Lee Shih-Wei, Fang Tuan-Jen, Hsu Ching-Wen, Li Hsueh-Yu

机构信息

Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC.

出版信息

Chang Gung Med J. 2003 Jan;26(1):65-9.

Abstract

Hypopharyngeal hemangiomas are uncommon neoplasms that can cause dysphagia, recurrent bleeding, and airway obstruction. These lesions are a therapeutic challenge, and surgical resection is the mainstay of therapy. The goal of therapy is directed at control of the tumor and relief of symptoms rather than total eradication of the lesion. Laser therapy is a very useful adjunct in the management of these vascular neoplasms. The neodymium: yttrium-aluminum-garnet laser (Nd:YAG laser) functions at a wavelength that provides deep thermal coagulation. This allows its use for these vascular lesions. With laser surgery, hemorrhage is the most frequent and dangerous complication, and its control is extremely important. Ligation and suture remain the traditional methods of hemostasis in most surgical situations. However, on certain occasions problems arise, particularly with large oozing surfaces or when surgical access is poor. Topical hemostatic agents are widely used in a variety of surgical procedures to successfully solve such problems. Microfibrillar collagen (Avitene) is one of the absorbable, topical, hemostatic agents, and is used effectively to control bleeding in many surgical situations. Since we began to use microfibrillar collagen (AviteneTM, MedchemProduct, Inc., Woburn, MA01801) to stop the massive oozing of the laser-induced surgical wound, no episodes of bleeding had ever occurred. It is concluded that Avitene is an effective agent for maintaining hemostasis in many surgical procedures, and we consider it a good remedy for management of laser-induced bleeding complications.

摘要

下咽血管瘤是一种罕见的肿瘤,可导致吞咽困难、反复出血和气道阻塞。这些病变是治疗上的一大挑战,手术切除是主要的治疗方法。治疗的目标是控制肿瘤和缓解症状,而不是彻底根除病变。激光治疗是这些血管性肿瘤治疗中非常有用的辅助手段。钕:钇铝石榴石激光(Nd:YAG激光)的作用波长能提供深部热凝固。这使得它可用于这些血管病变。在激光手术中,出血是最常见且危险的并发症,控制出血极为重要。在大多数手术情况下,结扎和缝合仍是传统的止血方法。然而,在某些情况下会出现问题,特别是在创面渗血量大或手术视野不佳时。局部止血剂在各种外科手术中被广泛使用以成功解决此类问题。微纤维胶原(可吸收明胶海绵)是一种可吸收的局部止血剂,在许多手术情况下能有效控制出血。自从我们开始使用微纤维胶原(可吸收明胶海绵TM,MedchemProduct公司,马萨诸塞州沃本01801)来止住激光手术创面的大量渗血后,从未发生过出血情况。得出结论,可吸收明胶海绵在许多外科手术中是维持止血的有效药物,我们认为它是处理激光所致出血并发症的良好药物。

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