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[局部止血剂阿维亭在泌尿外科手术中的临床研究]

[Clinical studies on topical hemostat Avitene in urological surgery].

作者信息

Kubo S, Ishibashi A, Koshiba K

出版信息

Hinyokika Kiyo. 1984 Jan;30(1):131-4.

PMID:6731191
Abstract

Avitene (Microfibrillar Collagen Hemostat) is a new absorbable topical hemostatic agent, of which action mechanisms are platelet entrapment and activation of platelet clotting factors. It was used clinically on 11 patients for bleeding during urological surgery; bleeding from renal beds, resectional surfaces of kidney, urethras and floor of the pelvis, prostatic capsule and renal pelvis. The patients were 9 males and 2 females aged from 30 to 71 years old. Avitene was applied directly to the source of bleeding in a dry condition after the treatment of large vessel hemostasis. Pressure was applied to the area, and after 3 to 5 minutes, the excess of this material was removed. Avitene was successful in rapidly controlling bleeding in all the patients. No patient had secondary bleeding and complications attributed to the use of this material. This study indicates that Avitene is very effective as a topical hemostatic agent, particularly in urological surgery.

摘要

爱维停(微纤维胶原止血剂)是一种新型可吸收局部止血剂,其作用机制是截留血小板并激活血小板凝血因子。它在临床上用于11例泌尿外科手术出血患者;包括肾床、肾脏切除创面、尿道和盆腔底部、前列腺包膜和肾盂出血。患者年龄在30至71岁之间,其中男性9例,女性2例。在处理大血管止血后,将爱维停在干燥状态下直接应用于出血部位。对该区域施加压力,3至5分钟后,去除多余的材料。爱维停成功地迅速控制了所有患者的出血。没有患者出现继发性出血以及因使用该材料导致的并发症。本研究表明,爱维停作为局部止血剂非常有效,尤其在泌尿外科手术中。

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