Weinryb Robert M, Liljeqvist Lars, Poppen Bertil, Gustavsson J Petter
Department of Clinical Neuroscience, Psychotherapy Section, Karolinska Institutet, Björngårdsgatan 25, SE-118 52 Stockholm, Sweden.
Am J Surg. 2003 Apr;185(4):333-8. doi: 10.1016/s0002-9610(02)01424-1.
There is a lack of longitudinal long-term studies of quality of life (QOL) after surgery with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis, where cohorts of patients are used as their own controls.
Forty ulcerative colitis patients who had undergone IPAA were prospectively assessed while they had a temporary ileostomy, and at a median of 18 months and 7 years after ileostomy closure. QOL was measured with the Psychosocial Adjustment to Illness Scale and the Well-Being Profile.
QOL was good at all three time points and, with some exceptions, did not change significantly between the assessments. There was a high degree of stability in the patients' evaluation of their QOL over time.
QOL was already good when the patients had a temporary ileostomy and generally did neither improve nor deteriorate during 7 years after ileostomy closure. QOL was also quite stable in terms of individual differences.
对于溃疡性结肠炎患者行回肠储袋肛管吻合术（IPAA）后生活质量（QOL）的纵向长期研究较少，此类研究将患者队列作为自身对照。
对40例行IPAA的溃疡性结肠炎患者进行前瞻性评估，评估时间点为患者行临时回肠造口术时、回肠造口关闭后中位数18个月和7年时。采用疾病心理社会适应量表和幸福概况量表测量生活质量。
在所有三个时间点生活质量均良好，除一些例外情况外，评估之间无显著变化。随着时间推移，患者对自身生活质量的评价具有高度稳定性。
患者行临时回肠造口术时生活质量已良好，回肠造口关闭后7年内通常既未改善也未恶化。生活质量在个体差异方面也相当稳定。
