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特发性艾迪生病中的人类白细胞抗原(HL-A)抗原

HL-A antigens in idiopathic Addison's disease.

作者信息

Ludwig H, Mayr W R, Pacher M, Schernthaner G, Koller K, Eibl M, Erd W

出版信息

Z Immunitatsforsch Exp Klin Immunol. 1975 Jul;149(5):423-7.

PMID:126574
Abstract

The frequencies of 36 HL-A antigens of the SD-1, SD-2 and SD-3 locus have been determined in 20 patients with idiopathic Addison's disease and compared with those of 450 controls. No significantly different HL-A antigen frequencies could be observed in both groups. These findings are in contradiction to data reported by a Copenhagen group. Possible mechanisms which might have led to this discrepancy are discussed.

摘要

已测定20例特发性艾迪生病患者SD-1、SD-2和SD-3位点的36种HL-A抗原的频率,并与450名对照者的频率进行比较。两组中未观察到HL-A抗原频率有显著差异。这些发现与哥本哈根一组报告的数据相矛盾。讨论了可能导致这种差异的机制。

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