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心外Fontan技术的比较:带蒂心包隧道与管道重建术

Comparison of extracardiac Fontan techniques: pedicled pericardial tunnel versus conduit reconstruction.

作者信息

Woods Ronald K, Dyamenahalli Umesh, Duncan Brian W, Rosenthal Geoffrey L, Lupinetti Flavian M

机构信息

Division of Pediatric Cardiothoracic Surgery, the University of Washington School of Medicine, Seattle, USA.

出版信息

J Thorac Cardiovasc Surg. 2003 Mar;125(3):465-71. doi: 10.1067/mtc.2003.153.

Abstract

OBJECTIVE

This study was designed to determine whether either of 2 alternative methods of extracardiac Fontan reconstruction provides superior results.

METHODS

We reviewed 58 consecutive Fontan procedures performed between 1995 and 2001 with a pedicled pericardial tunnel (group P, n = 21) or an extracardiac conduit of polytetrafluoroethylene or allograft aorta (group C, n = 37). Operations were performed with cardiopulmonary bypass at 32 degrees C; an aortic crossclamp was applied in only 6 patients. All group P patients and 33 (89%) group C patients received fenestrations.

RESULTS

The groups were similar in terms of age, weight, anatomy, and preoperative hemodynamics. There were 3 hospital deaths (5%; 70% confidence limit, 2%-30%), all in group C. Median durations of mechanical ventilation (group P, 1 day; group C, 1 day), intensive care unit stay (group P, 3 days; group C, 3 days), chest tube drainage (group P, 8 days; group C, 7 days), and hospitalization (group P, 10 days; group C, 9 days) were not significantly different. There were no late deaths. All patients received warfarin sodium, and there were no late strokes. Before the Fontan procedure, 1 patient in group P and 3 patients in group C required pacemaker implants. Of the 51 surviving patients in sinus rhythm before the Fontan procedure, only 1 patient in group C subsequently required a pacemaker.

CONCLUSIONS

Extracardiac Fontan procedures with either a pericardial baffle or conduit are associated with low operative mortality and low risks of arrhythmia and late thromboembolic complication.

摘要

目的

本研究旨在确定两种心外法洛四联症重建替代方法中的任何一种是否能提供更好的结果。

方法

我们回顾了1995年至2001年间连续进行的58例法洛四联症手术,其中采用带蒂心包隧道(P组,n = 21)或聚四氟乙烯或同种异体主动脉心外管道(C组,n = 37)。手术在32℃体外循环下进行;仅6例患者应用了主动脉阻断钳。所有P组患者和33例(89%)C组患者接受了开窗术。

结果

两组在年龄、体重、解剖结构和术前血流动力学方面相似。有3例医院死亡(5%;70%置信区间,2%-30%),均在C组。机械通气的中位持续时间(P组,1天;C组,1天)、重症监护病房停留时间(P组,3天;C组,3天)、胸管引流时间(P组,8天;C组,7天)和住院时间(P组,10天;C组,9天)无显著差异。无晚期死亡。所有患者均接受华法林钠治疗,无晚期卒中。在法洛四联症手术前,P组有1例患者和C组有3例患者需要植入起搏器。在法洛四联症手术前窦性心律的51例存活患者中,C组只有1例患者随后需要起搏器。

结论

采用心包挡板或管道的心外法洛四联症手术与低手术死亡率、低心律失常风险和晚期血栓栓塞并发症风险相关。

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