功能性单心室患儿的当前治疗与预后
Current treatment and prognosis in children with functionally univentricular hearts.
作者信息
Kaulitz R, Hofbeck M
机构信息
Department of Pediatric Cardiology and Pediatric Intensive Care Medicine, Tuebingen University Hospital, Germany.
出版信息
Arch Dis Child. 2005 Jul;90(7):757-62. doi: 10.1136/adc.2003.034090.
Abstract
For more than 30 years Fontan-type procedures have been performed for surgical treatment in patients with functionally univentricular hearts. Advances in proper patient selection, staging of the Fontan palliation, and modifications of the surgical technique resulted in continuous improvement of the surgical results during the past two decades. However, increasing experience with medium term and long term follow-up of the Fontan circulation has drawn attention to a number of sequelae and chronic complications affecting a significant number of patients.
摘要
30多年来，Fontan类手术一直用于功能性单心室心脏患者的外科治疗。在过去二十年中，合适的患者选择、Fontan姑息手术分期以及手术技术改良方面的进展使得手术效果不断改善。然而，随着对Fontan循环中期和长期随访经验的增加，一些后遗症和慢性并发症引起了关注，这些并发症影响着大量患者。
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Procoagulant and anticoagulant factor abnormalities following the Fontan procedure: increased factor VIII may predispose to thrombosis.Fontan手术后促凝血和抗凝血因子异常：因子VIII增加可能易导致血栓形成。
J Thorac Cardiovasc Surg. 2003 Jun;125(6):1260-7. doi: 10.1016/s0022-5223(02)73605-2.
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