Ikai Akio, Fujimoto Yoshifumi, Hirose Keiichi, Ota Noritaka, Tosaka Yuko, Nakata Tomohiro, Ide Yujiro, Sakamoto Kisaburo
Department of Cardiovascular Surgery, Iwate Medical University Memorial Heart Center, Shizuoka, Japan.
J Thorac Cardiovasc Surg. 2008 May;135(5):1145-52. doi: 10.1016/j.jtcvs.2007.12.013.
The extracardiac conduit Fontan procedure has led to improved outcomes. We performed the procedure in patients weighing less than 10 kg and evaluated its feasibility.
Since January 1999, 72 patients weighing less than 20 kg underwent extracardiac conduit Fontan procedure with polytetrafluoroethylene conduits. The patients were divided into 2 groups: 36 patients weighing less than 10 kg in group S and 36 weighing more than 10 kg in group L. Mean weight, median age, and median follow-up period in groups S and L were 8.5 +/- 1.1 and 14.0 +/- 3.0 kg, 18.9 and 42.0 months, and 29.2 (1.7-79.7) and 42.1 (2.8-94.2) months, respectively. Postoperatively, most patients received peritoneal drainage catheters. We reviewed data precatheterization and postcatheterization and postoperative course.
Conduit sizes in groups S and L were 17.0 +/- 1.3 and 17.9 +/- 1.9 mm, respectively (P = .03). Five patients required fenestrations. There were 2 hospital deaths, 1 in each group, and 2 late deaths in group S. The postoperative course was identical in both groups, except for median length of stay in the intensive care unit and peritoneal drainage volume. Group S versus L: ventilator support, 11 versus 7 hours; pleural drainage, 9 days each; pleural drainage greater than 14 days, 6 versus 5 cases; peritoneal drainage, 8 versus 7 days; intensive care unit stay, 7 versus 4 days (P = .01), peritoneal drainage volume, 26.1 versus 14.1 mL x kg x d(-1) (P = .0007).
The early outcome of the extracardiac conduit Fontan procedure was satisfactory in patients weighing less than 10 kg. However, the required size of the conduit remains debatable.
心外管道Fontan手术已使治疗效果得到改善。我们对体重不足10kg的患者实施了该手术,并评估其可行性。
自1999年1月起,72例体重不足20kg的患者接受了使用聚四氟乙烯管道的心外管道Fontan手术。患者被分为2组:S组36例体重不足10kg,L组36例体重超过10kg。S组和L组的平均体重、年龄中位数和随访期中位数分别为8.5±1.1和14.0±3.0kg、18.9和42.0个月、29.2(1.7 - 79.7)和42.1(2.8 - 94.2)个月。术后,大多数患者留置了腹腔引流管。我们回顾了置管前、置管后及术后病程的数据。
S组和L组的管道尺寸分别为17.0±1.3和17.9±1.9mm(P = 0.03)。5例患者需要开窗。有2例住院死亡,每组各1例,S组有2例晚期死亡。两组术后病程相同,但重症监护病房停留时间中位数和腹腔引流量除外。S组与L组比较:呼吸机支持时间,11小时对7小时;胸腔引流,均为9天;胸腔引流超过14天,6例对5例;腹腔引流,8天对7天;重症监护病房停留时间,7天对4天(P = 0.01),腹腔引流量,26.1对14.1mL·kg·d⁻¹(P = 0.0007)。
对于体重不足10kg的患者,心外管道Fontan手术的早期效果令人满意。然而,所需管道的尺寸仍存在争议。