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曼氏血吸虫感染人类和小鼠中的血吸虫色素

Schistosomal pigment in human and murine infections with Schistosoma mansoni.

作者信息

Grimaud J A, Borojevic R, Araujo Dos Santos H

出版信息

Trans R Soc Trop Med Hyg. 1976;70(1):73-7. doi: 10.1016/0035-9203(76)90011-0.

DOI:10.1016/0035-9203(76)90011-0
PMID:1265822
Abstract

Schistosomal pigment was studied by optical and electron microscopy in liver biopsies of patients with different clinical forms of schistosomiasis and in livers of mice experimentally infected with Schistosoma mansoni. Phagosomal and residual forms of the pigment are described. The quantity of pigment is low in subclinical and in hepatointestinal forms of schistosomiasis; it is high in young patients with the hepatosplenic form, and low in the old ones. The participation of the pigment in the pathogenesis of schistosomal lesions is discussed.

摘要

通过光学显微镜和电子显微镜对不同临床类型血吸虫病患者的肝活检组织以及实验感染曼氏血吸虫的小鼠肝脏中的血吸虫色素进行了研究。描述了色素的吞噬体形式和残余形式。在亚临床型和肝肠型血吸虫病中色素量较低;在肝脾型的年轻患者中色素量较高,而在老年患者中色素量较低。本文还讨论了色素在血吸虫病病变发病机制中的作用。

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Schistosomal pigment in human and murine infections with Schistosoma mansoni.曼氏血吸虫感染人类和小鼠中的血吸虫色素
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引用本文的文献

1
Hepatic eosinophil granulocytopoiesis in murine experimental Schistosomiasis mansoni.小鼠实验性曼氏血吸虫病中的肝脏嗜酸性粒细胞生成
Br J Exp Pathol. 1981 Oct;62(5):480-9.
2
Unisexual murine schistosomiasis: portal hepatitis in subacute infections.
Experientia. 1985 Nov 15;41(11):1423-6. doi: 10.1007/BF01950016.
3
IgG deposits and Disse's space pathology in human schistosomal liver.人类血吸虫性肝病中的IgG沉积及狄氏间隙病理改变
Experientia. 1977 Aug 15;33(8):1078-9. doi: 10.1007/BF01945980.
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Myofibroblasts in hepatic schistosomal fibrosis.肝血吸虫病纤维化中的肌成纤维细胞
Experientia. 1977 Jul 15;33(7):890-2. doi: 10.1007/BF01951264.