Ji Ruiping, Wang Xinfang, Cheng Tsung O, Liu Wangpeng, Li Zhi'an, Liu Li
Institute of Cardiology, Xiehe Hospital, Tongji Medical College, Huazhoong University of Science and Technology, Wuhan 430030.
J Huazhong Univ Sci Technolog Med Sci. 2002;22(1):52-7. doi: 10.1007/BF02904789.
To evaluate the possibility and accuracy of Doppler tissue image (DTI) on assessment of normal and abnormal ventricular activation and contraction sequence, 9 open chest canine hearts were analyzed by acceleration mode, M-mode, and spectrum mode DTI. Our results showed that: (1) Acceleration mode DTI could show the origin of activation and conduction sequence on line; (2) M-mode DTI revealed that the activation in mid-interventricular septum was earlier than that in mid-left ventricular posterior wall at sinus activation; (3) Spectrum DTI showed the ventricular endocardium was activated earlier than the ventricular epicardium in all segments at sinus rhythm. The earliest site of activation of the normal ventricular wall was at middle interventricular septum; the latest site was at basal-posterior wall; the contraction sequence was different at the different walls; (4) During abnormal ventricular activation, mid-left ventricular posterior wall was activated earliest in accordance with the pacing sites. Abnormal ventricular activation was slower than sinus activation, and the contraction sequence varied at different sites of ventricular wall. It is concluded that DTI can be used to localize the origin of normal or abnormal myocardial activation and to assess the contraction sequence conveniently, accurately and non-invasively.
为评估多普勒组织成像（DTI）在评估正常及异常心室激动和收缩顺序方面的可能性及准确性，采用加速度模式、M型及频谱模式DTI对9只开胸犬心脏进行了分析。我们的结果显示：（1）加速度模式DTI可在线显示激动起源及传导顺序；（2）M型DTI显示，窦性激动时室间隔中部的激动早于左心室后壁中部；（3）频谱DTI显示，窦性心律时所有节段的心内膜激动均早于心外膜。正常心室壁最早激动部位位于室间隔中部；最晚激动部位位于心底后壁；不同心室壁的收缩顺序不同；（4）在异常心室激动时，左心室后壁中部根据起搏部位最早激动。异常心室激动比窦性激动慢，且心室壁不同部位的收缩顺序各异。结论是DTI可用于定位正常或异常心肌激动的起源，并方便、准确且无创地评估收缩顺序。
