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[评估分娩单位规模对新生儿生存的影响:1990 - 2000年德国黑森州潜在可避免死亡的估计]

[Assessing the impact of delivery unit size on neonatal survival: estimation of potentially avoidable deaths in Hessen, Germany, 1990-2000].

作者信息

Heller G, Schnell R, Richardson D K, Misselwitz B, Schmidt S

机构信息

Klinik für Geburtshilfe und Perinatologie, Zentrum für Gynäkologie und Geburtshilfe, Universität Marburg.

出版信息

Dtsch Med Wochenschr. 2003 Mar 28;128(13):657-62. doi: 10.1055/s-2003-38284.

Abstract

BACKGROUND AND OBJECTIVE

There are only few analyses from Germany on the impact of delivery unit size on neonatal outcome. The objective of this study was to evaluate the influence of delivery unit size on neonatal survival in Germany.

PATIENTS AND METHODS

Data from the perinatal birth register for Hessen for 1990-2000 comprising 640554 births, and the Neonatal Survey for 1989-1997 in Hessen were used. Potentially avoidable deaths were assessed according to delivery unit size and birth weight category. Additionally trend analyses and an extrapolation to potentially avoidable deaths in all of Germany were performed.

RESULTS

Compared to large delivery units, smaller ones showed higher risk adjusted mortality rates. Calculation of potentially avoidable deaths gave an estimate of 257 early neonatal deaths in 11 years. Although trend analyses revealed a decline of potentially avoidable deaths, an extrapolation of such deaths for all of Germany still yielded an estimate of more than 300 potentially avoidable deaths per year using data from 1997-2000 only.

CONCLUSION

A valid inference as to the magnitude of the observed effect remains even in the face of a very cautious interpretation of our results. During the study period of 11 years, more than 200 neonatal deaths could be attributed to the fact that births in Hessen are dispersed among many small hospitals. If this pattern of births in small units is common throughout Germany, it suggests that several hundred neonatal deaths per year may be attributed to this risk factor when extrapolating these results nationally. Further research is necessary to describe the nation-wide magnitude of this problem and to identify the role of underlying causal risk factors more precisely. Additionally policy discussions regarding structural changes in obstetrical care should be undertaken in the meantime, aimed at reducing the observed mortality rates.

摘要

背景与目的

德国仅有少数关于分娩单位规模对新生儿结局影响的分析。本研究的目的是评估德国分娩单位规模对新生儿存活的影响。

患者与方法

使用了黑森州1990 - 2000年围产期出生登记册中的数据,包括640554例分娩,以及1989 - 1997年黑森州的新生儿调查数据。根据分娩单位规模和出生体重类别评估潜在可避免死亡。此外,还进行了趋势分析,并外推至德国所有地区的潜在可避免死亡情况。

结果

与大型分娩单位相比,小型分娩单位的风险调整死亡率更高。潜在可避免死亡的计算得出11年中有257例早期新生儿死亡的估计值。尽管趋势分析显示潜在可避免死亡有所下降,但仅使用1997 - 2000年的数据对德国所有地区此类死亡进行外推,每年仍得出超过300例潜在可避免死亡的估计值。

结论

即使对我们的结果进行非常谨慎的解释,对于所观察到的效应大小仍能得出有效推断。在11年的研究期间,超过200例新生儿死亡可归因于黑森州的分娩分散在许多小医院这一事实。如果德国各地小型单位的这种分娩模式普遍存在,那么将这些结果外推至全国时,表明每年可能有数百例新生儿死亡可归因于这一风险因素。有必要进行进一步研究以描述该问题在全国范围内的严重程度,并更精确地确定潜在因果风险因素的作用。此外,与此同时应就产科护理的结构变化进行政策讨论,以降低所观察到的死亡率。

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