两名孕早期未治疗的甲状腺功能亢进症女性所生婴儿的胃肠道畸形。
Gastrointestinal malformations in two infants born to women with hyperthyroidism untreated in the first trimester.
作者信息
Seoud Muhieddine, Nassar Anwar, Usta Ihab, Mansour Mohammad, Salti Ibrahim, Younes Khaled
机构信息
Obstetrics and Gynecology, The American University of Beirut Medical Center, New York, New York 10022, USA.
出版信息
Am J Perinatol. 2003 Feb;20(2):59-62. doi: 10.1055/s-2003-38320.
We report two infants with gastrointestinal anomalies: one with esophageal atresia and tracheo-esophageal fistula and the other with biliary tree atresia, born to hyperthyroid women diagnosed and treated with methimazole after 14 weeks' gestation. Euthyroidism was documented in both infants. These cases raise the issue of whether untreated hyperthyroidism and not methimazole intake is the teratogen.
我们报告了两名患有胃肠道异常的婴儿
一名患有食管闭锁和气管食管瘘，另一名患有胆道闭锁，他们的母亲均为甲状腺功能亢进症患者，在妊娠14周后确诊并接受甲巯咪唑治疗。两名婴儿均记录为甲状腺功能正常。这些病例引发了一个问题，即致畸因素是未治疗的甲状腺功能亢进症而非甲巯咪唑的摄入。
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