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[良性乳腺疾病:临床、影像学与病理学相关性]

[Benign breast diseases: clinical, radiological and pathological correlation].

作者信息

Murillo Ortiz Blanca, Botello Hernández Daniel, Ramírez Mateos Carlos, Reynaga García Francisco Javier

出版信息

Ginecol Obstet Mex. 2002 Dec;70:613-8.

Abstract

INTRODUCTION

Benign lesions of the breast are common; however, benign pathological states have always been neglected in comparison to cancer even though they account for as much as 90 percent of the clinical presentations related to breast. A useful classification system for benign breast disease has been described by Love and colleagues and is based on symptoms and physical findings, six general categories have been identified, which include physiological swelling and tenderness, nodularity, mastalgia, dominant lumps, nipple discharge, and inflammation. Another classification system developed by Page and coworkers separates the various types of benign breast lesions into three clinically relevant groups: non-proliferative lesions, proliferative lesions without atypia, and proliferative the histopathological evaluation of the biopsy specimen in order to determine the subsequent risk of developing carcinoma if the lesions represents atypia of lobules or ductal epithelium.

OBJECTIVE

The study was made to evaluate the clinical, radiological and pathological correlation of the benign breast lesions.

METHODS

We studied women aged 40 years or less that went to the Foundation Rodolfo Padilla Padilla by mastalgia or the presence of a mass. We determined the Kappa coefficient in order to identify the agreement between the three observers according to different pathologies: fibroadenoma, abscess, cyst, mastitis, fibrosis, and cancer.

RESULTS

We made 698 breast Ultrasounds in women younger 40 years, we found 52% ultrasound normal and 48% were reported with benign breast pathology: fibroadenomas 38%, cyst 27%, dilated ducts 24%, benign nodule 4%, mastitis 3%, ectasia 2%, and abscess 2%. The correlation was made to 58 patients, finding the following coefficients kappa. Fibroadenoma: when evaluating the clinical examination versus ultrasound: K = 50%. Cysts: when evaluating clinical examination versus ultrasound: K = 17%, when evaluating ultrasound versus pathology: K = 3%. Fibrosis: when evaluating clinical examination versus ultrasound: K = 56%, when evaluating ultrasound versus pathology: K = 50%, when evaluating ultrasound versus pathology: K = 50%.

CONCLUSION

The benign breast pathology must be studied carefully because the clinical and ultrasonic evaluation is not conclusive, and the histopathological evaluation of the biopsy specimens sometimes is necessary to discard malignancy.

摘要

引言

乳腺良性病变很常见;然而,尽管良性病理状态占乳腺相关临床表现的90%,但与癌症相比,它们一直被忽视。洛夫及其同事描述了一种有用的乳腺良性疾病分类系统,该系统基于症状和体格检查结果,确定了六个一般类别,包括生理性肿胀和压痛、结节性、乳腺疼痛、优势肿块、乳头溢液和炎症。佩奇及其同事开发的另一种分类系统将各种类型的乳腺良性病变分为三个临床相关组:非增生性病变、无非典型增生的增生性病变以及伴有小叶或导管上皮非典型增生的增生性病变。活检标本的组织病理学评估是为了确定如果病变代表小叶或导管上皮非典型增生,随后发生癌变的风险。

目的

本研究旨在评估乳腺良性病变的临床、影像学和病理学相关性。

方法

我们研究了年龄在40岁及以下因乳腺疼痛或有肿块前往鲁道夫·帕迪利亚基金会就诊的女性。我们确定了卡帕系数,以便根据不同病理(纤维腺瘤、脓肿、囊肿、乳腺炎、纤维化和癌症)确定三位观察者之间的一致性。

结果

我们对40岁以下女性进行了698次乳腺超声检查,发现52%的超声检查结果正常,48%的报告有乳腺良性病变:纤维腺瘤38%、囊肿27%、扩张导管24%、良性结节4%、乳腺炎3%、扩张2%、脓肿2%。对58名患者进行了相关性分析,得出以下卡帕系数。纤维腺瘤:评估临床检查与超声检查时:K = 50%。囊肿:评估临床检查与超声检查时:K = 17%,评估超声检查与病理检查时:K = 3%。纤维化:评估临床检查与超声检查时:K = 56%,评估超声检查与病理检查时:K = 50%,评估超声检查与病理检查时:K = 50%。

结论

必须仔细研究乳腺良性病变,因为临床和超声评估并不具有决定性,有时需要对活检标本进行组织病理学评估以排除恶性肿瘤。

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