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脑膜血管外皮细胞瘤:三例报告并文献复习

Meningioangiomatosis: report of three cases and review of the literature.

作者信息

Savargaonkar Pratima, Chen Sheng, Bhuiya Tawfiqal, Valderrama Elsa, Bloom Tamara, Farmer Peter M

机构信息

Albert Einstein School of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.

出版信息

Ann Clin Lab Sci. 2003 Winter;33(1):115-8.

Abstract

Meningioangiomatosis is a rare condition, probably hamartomatous, characterized by proliferation of capillary-sized vessels, meningothelial cells, and fibroblasts within the cortex of the brain. Lesions may be single or diffuse and may be associated with neurofibromatosis type II. Clinically it presents with seizures but may be asymptomatic throughout life. We report 3 cases of meningioangiomatosis, 2 localized and 1 diffuse, all with different clinical manifestations. Differential diagnoses are discussed with a review of the literature. Since this condition is rare, close clinico-pathological correlation is essential. A correct diagnosis avoids further aggressive treatment.

摘要

脑膜血管外皮细胞瘤是一种罕见的疾病,可能为错构瘤,其特征是脑皮质内毛细血管大小的血管、脑膜内皮细胞和成纤维细胞增生。病变可为单发或弥漫性,可能与II型神经纤维瘤病相关。临床上表现为癫痫发作,但也可能终生无症状。我们报告3例脑膜血管外皮细胞瘤,2例为局限性,1例为弥漫性,均有不同的临床表现。结合文献复习讨论了鉴别诊断。由于这种疾病罕见,密切的临床病理相关性至关重要。正确的诊断可避免进一步的积极治疗。

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