Kashlan Osama N, Laborde David V, Davison Lakesha, Saindane Amit M, Brat Daniel, Hudgins Patricia A, Gross Robert E
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
Case Rep Neurol Med. 2011;2011:361203. doi: 10.1155/2011/361203. Epub 2011 Oct 9.
Purpose. Meningioangiomatosis (MA) is a rare, benign lesion that commonly mimics other intracranial malformations in clinical presentation and appearance on imaging. The case presented and the literature review performed highlight the importance of combining MRI and CT results to better characterize intracranial lesions and including MA on the list of differential diagnoses of patients presenting with seizures. Methods. The case described is of a 19-year-old male with a 10-year history of worsening seizures refractory to multiple drug regimens. MRI revealed an atypical vascular malformation. The patient underwent surgical resection of the epileptogenic cortex. Results. Although the radiologic impression of the lesion was a vascular malformation, pathological examination revealed MA. A literature search performed highlights the variability of the appearance of MA on CT and MRI and suggests the utility of the T2 GRE sequence in illustrating the presence of calcification and, in a lesion with other characteristic features, the diagnosis of MA. Conclusion. MA can be a difficult diagnosis to make based on imaging findings alone. However, in a patient with a characteristic history and presentation, the presence of a calcified mass on CT and MRI brain susceptibility artifact on a T2 GRE sequence may suggest MA.
目的。脑膜血管外皮细胞瘤(MA)是一种罕见的良性病变,在临床表现和影像学表现上通常与其他颅内畸形相似。所呈现的病例及进行的文献综述强调了结合MRI和CT结果以更好地描述颅内病变的重要性,并将MA纳入癫痫发作患者的鉴别诊断清单。方法。所描述的病例是一名19岁男性,有10年癫痫发作加重病史,多种药物治疗方案均无效。MRI显示为非典型血管畸形。患者接受了致痫皮层的手术切除。结果。尽管病变的放射学印象是血管畸形,但病理检查显示为MA。进行的文献检索突出了MA在CT和MRI上表现的变异性,并提示T2 GRE序列在显示钙化存在方面的实用性,以及在具有其他特征性表现的病变中对MA诊断的实用性。结论。仅根据影像学表现,MA可能难以诊断。然而,在具有特征性病史和表现的患者中,CT上出现钙化肿块以及T2 GRE序列上MRI脑磁敏感伪影可能提示MA。