Paulsen S, Vetner M, Hagerup L M
Acta Pathol Microbiol Scand A. 1975 Sep;83(5):429-32. doi: 10.1111/j.1699-0463.1975.tb00153.x.
Sex variation in the area of the coronary ostia was studied in hearts with a normal weight (heart weight less than 400 g) and hypertrophic hearts (heart weight greater than or equal to 400 g). Also studied was a possible sex difference in the correlation between heart weight and the area of the coronary ostia. The study was performed on 379 post mortem hearts. In the group of hearts with a normal weight the area of the left coronary ostium in both sexes was greater than the right but the difference was statistically insignificant. There was no sex difference in the area of the left coronary ostium, whereas the area of the right coronary ostium was statistically significantly less in women. In the group of hyperthopic hearts the left coronary ostium increased in area with increasing heart weight. The difference in the area of the left coronary ostium between hearts with normal weight and hypertrophic hearts was stastically significant in men, but not in women. The right coronary ostium showed minimal increase in size with increasing heart weight and the difference in both sexes between the two groups was statistically insignificant. In the group of hypertrophic hearts the heart weight was best correlated to the area of the left coronary ostium in both sexes, but the values did not reach statistically significance. On the basis of this study the area of the right coronary ostium appears to be a bottleneck with regard to an adequate blood supply to a hypertrophic myocardium.
对正常体重心脏（心脏重量小于400克）和肥厚性心脏（心脏重量大于或等于400克）的冠状动脉口面积的性别差异进行了研究。还研究了心脏重量与冠状动脉口面积之间相关性的可能性别差异。该研究在379个尸检心脏上进行。在正常体重心脏组中，两性的左冠状动脉口面积均大于右冠状动脉口面积，但差异无统计学意义。左冠状动脉口面积无性别差异，而女性的右冠状动脉口面积在统计学上显著更小。在肥厚性心脏组中，左冠状动脉口面积随心脏重量增加而增大。正常体重心脏与肥厚性心脏的左冠状动脉口面积差异在男性中具有统计学意义，但在女性中无统计学意义。右冠状动脉口大小随心脏重量增加而增加最小，两组两性之间的差异无统计学意义。在肥厚性心脏组中，心脏重量与两性的左冠状动脉口面积相关性最佳，但这些值未达到统计学意义。基于这项研究，右冠状动脉口面积似乎是肥厚性心肌充足血液供应的一个瓶颈。
