Maldonado Mario R, Chong Erica R, Oehl Melissa A, Balasubramanyam Ashok
Division of Endocrinology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Diabetes Care. 2003 Apr;26(4):1265-9. doi: 10.2337/diacare.26.4.1265.
Diabetic ketoacidosis (DKA) is a common complication of diabetes. We analyzed the inpatient costs of treating DKA in a multiethnic, indigent population in Houston, Texas.
We measured the cost of resources utilized for all patients admitted to our hospital with DKA from 1 January to 31 December 1998. We also analyzed their medical records to determine the factors that precipitated the episode of DKA and then grouped them into three categories: acute illnesses, noncompliance with diabetes treatment, and new-onset diabetes. The data were analyzed by one-way ANOVA. The Tukey-Kramer procedure was used for post hoc multiple comparisons.
There were 167 admissions for DKA. The mean age was 40 +/- 13 years. The ethnic distribution was 49% African American, 32% Hispanic American, and 18% white. The total inhospital cost of treating DKA was $1,816,255. The mean cost per hospitalization was $10, 876 +/- 11,024. The frequency distribution by category of DKA-precipitating factor was 18% acute illness, 59% noncompliance, and 23% new onset. There were differences in mean cost of DKA associated with the three categories: $20,864 +/- 17,910 for acute illness, $11,863 +/- 8,701 for new onset, and $7,470 +/- 6,300 for noncompliance (P < 0.0001). The total cost for each category was $671,375 for acute illness, $694,082 for noncompliance, and $450,798 for new onset.
DKA is an expensive complication among indigent, multiethnic diabetic patients. Although the mean cost per admission was lowest for DKA precipitated by noncompliance, this causal category was responsible in sum for the greatest portion of the economic burden.
糖尿病酮症酸中毒(DKA)是糖尿病的常见并发症。我们分析了得克萨斯州休斯顿市一个多民族贫困人群中DKA的住院治疗费用。
我们测算1998年1月1日至12月31日期间我院收治的所有DKA患者所使用资源的费用。我们还分析他们的病历以确定引发DKA发作的因素,然后将其分为三类:急性疾病、糖尿病治疗依从性差和新发糖尿病。数据采用单因素方差分析进行分析。Tukey-Kramer法用于事后多重比较。
共有167例DKA患者入院。平均年龄为40±13岁。种族分布为49%非裔美国人、32%西班牙裔美国人、18%白人。治疗DKA的住院总费用为1,816,255美元。每次住院的平均费用为10,876±11,024美元。按DKA诱发因素类别划分的频率分布为:急性疾病占18%,治疗依从性差占59%,新发糖尿病占23%。与这三类因素相关的DKA平均费用存在差异:急性疾病为20,864±17,910美元,新发糖尿病为11,863±8,701美元,治疗依从性差为7,470±6,300美元(P<0.0001)。各类别的总费用分别为:急性疾病671,375美元,治疗依从性差694,082美元,新发糖尿病450,798美元。
DKA在贫困的多民族糖尿病患者中是一种费用高昂的并发症。尽管因治疗依从性差引发的DKA每次住院的平均费用最低,但这一病因类别在经济负担中所占的总和比例最大。