罕见三联征：高钙血症诱发坏死性胰腺炎，表现为严重糖尿病酮症酸中毒。
A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis.
机构信息
Morehouse School of Medicine, Atlanta, GA, USA.
出版信息
J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:2324709621998477. doi: 10.1177/2324709621998477.
Primary hyperparathyroidism (PHPT) typically occurs in persons above 45 years, with a female predominance. PHPT induces a state of hypercalcemia, but acute pancreatitis is a rare sequelae of this hypercalcemia. We report a case of a 31-year-old man with no known medical history who presented in diabetic ketoacidosis with electrolyte abnormalities. His clinical course progressed to multi-organ dysfunction despite correction of metabolic derangements. Further workup led to the discovery of the uncommon triad by which previously undiagnosed PHPT precipitated severe diabetic ketoacidosis.
原发性甲状旁腺功能亢进症（PHPT）通常发生在 45 岁以上的人群中，女性多见。PHPT 可导致高钙血症，但急性胰腺炎是这种高钙血症的罕见后遗症。我们报告了一例 31 岁男性的病例，该患者无已知病史，以糖尿病酮症酸中毒伴电解质异常就诊。尽管代谢紊乱得到纠正，但他的临床病程仍进展为多器官功能障碍。进一步的检查发现了一组不常见的三联征，即先前未诊断的 PHPT 引发了严重的糖尿病酮症酸中毒。
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