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用于血液透析的头臂动静脉内瘘与肱动脉-尺侧副动脉内瘘结局的前瞻性比较

A Prospective Comparison of Outcomes of Brachiocephalic Versus Brachiobasilic Fistulas for Hemodialysis.

作者信息

John Joel Mathew, Mithra Lam Samuel Prabhu, Reddy Yeddula Gnanendra, Selvaraj Andrew Dheepak, Premkumar Prabhu, Samuel Vimalin

机构信息

Department of Vascular Surgery, Christian Medical College Vellore, Vellore, Tamil Nadu, India.

出版信息

Indian J Nephrol. 2025 Jan-Feb;35(1):40-45. doi: 10.25259/ijn_367_23. Epub 2024 Jul 1.

Abstract

BACKGROUND

Brachiocephalic fistula (BCF) and brachiobasilic fistula (BBF) are autogenous fistulas created in the arm for hemodialysis access. However, despite the differences in anatomy and surgical technique, the existing literature shows no significant statistical difference between the maturation, patency, or complications. We analyzed the outcomes of these two types of arteriovenous fistulas in our subgroup of the Indian population.

MATERIALS AND METHODS

A prospective observational cohort study was performed at a tertiary hospital from August 2019 to August 2021 between patients who underwent BCF and BBF. The time to maturation, 1-year primary patency, and postoperative complications were studied.

RESULTS

Among the 236 patients, 137 and 99 underwent BCF and BBF, respectively. 53 (39%) and 37 (37.4%) patients were lost to follow-up at the end of 12 months in each arm, respectively. Each group comprised predominantly of males. There was no significant difference in age, diabetes, coronary artery disease, or peripheral arterial disease between the groups. The time to maturation within 6 weeks, more than 6 weeks, and non-maturation was 51.88% and 58.1% (p = 0.58), 38.67% and 32.55% (p = 0.04), and 9.43% and 9.3% (p = 0.74) in BCF and BBF groups, respectively. The 1-year primary patency, primary-assisted patency, and secondary patency were 69.04% and 53.22% (p <0.001), 78.3% and 59.6%, and 79.5% and 62.9% in BCF and BBF groups, respectively. Apart from venous hypertension (BCF:2(1.5%) vs BBF:7(7.1%), p = 0.026), there were no significant differences in the postoperative complications between the groups.

CONCLUSION

BCFs take longer to mature but have greater primary patency than BBF. Both of these fistulas had similar postoperative complications. Larger randomized trials are needed to confirm our findings.

摘要

背景

头臂瘘(BCF)和肱桡瘘(BBF)是在手臂上创建的自体瘘,用于血液透析通路。然而,尽管在解剖结构和手术技术上存在差异,但现有文献表明,在成熟度、通畅率或并发症方面没有显著的统计学差异。我们分析了印度人群亚组中这两种类型动静脉瘘的治疗结果。

材料与方法

2019年8月至2021年8月,在一家三级医院对接受BCF和BBF手术的患者进行了一项前瞻性观察队列研究。研究了成熟时间、1年原发性通畅率和术后并发症。

结果

在236例患者中,分别有137例和99例接受了BCF和BBF手术。每组分别有53例(39%)和37例(37.4%)患者在12个月结束时失访。每组主要为男性。两组在年龄、糖尿病、冠状动脉疾病或外周动脉疾病方面无显著差异。BCF组和BBF组在6周内成熟、超过6周成熟和未成熟的时间分别为51.88%和58.1%(p = 0.58)、38.67%和32.55%(p = 0.04)、9.43%和9.3%(p = 0.74)。BCF组和BBF组的1年原发性通畅率、原发性辅助通畅率和继发性通畅率分别为69.04%和53.22%(p <0.001)、78.3%和59.6%、79.5%和62.9%。除静脉高压外(BCF:2例(1.5%) vs BBF:7例(7.1%),p = 0.026),两组术后并发症无显著差异。

结论

BCF成熟所需时间更长,但原发性通畅率高于BBF。这两种瘘的术后并发症相似。需要更大规模的随机试验来证实我们的发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/11762823/4d4a1360a07c/IJN-35-1-40-g1.jpg

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